نتایج جستجو برای: radial arm maze

تعداد نتایج: 137875  

2017
Devin Wahl Sean CP Coogan Samantha M Solon-Biet Rafael de Cabo James B Haran David Raubenheimer Victoria C Cogger Mark P Mattson Stephen J Simpson David G Le Couteur

Evaluation of behavior and cognition in rodent models underpins mechanistic and interventional studies of brain aging and neurodegenerative diseases, especially dementia. Commonly used tests include Morris water maze, Barnes maze, object recognition, fear conditioning, radial arm water maze, and Y maze. Each of these tests reflects some aspects of human memory including episodic memory, recogni...

Journal: :basic and clinical neuroscience 0
pamphyle abedi mukutenga khalid taghzouti wail a. bengelloun

introduction: the dorsal striatum plays an important role in the control of motor activity and learning processes within the basal ganglia circuitry. furthermore, recent works have suggested functional differentiation between subregions of the dorsal striatum methods: the present study examined the effects of bilateral electrolytic lesions of the dorsomedial striatum on motor behavior and learn...

2017
Jason C. D. Nguyen Saher F. Ali Sepideh Kosari Owen L. Woodman Sarah J. Spencer A. Simon Killcross Trisha A. Jenkins

Rats fed high fat diets have been shown to be impaired in hippocampal-dependent behavioral tasks, such as spatial recognition in the Y-maze and reference memory in the Morris water maze (MWM). It is clear from previous studies, however, that motivation and reward factor into the memory deficits associated with obesity and high-fat diet consumption, and that the prefrontal cortex and striatum an...

Journal: :Behavioural brain research 2005
Noah J Sandstrom Sarah R Hart

Stressful experiences during development cause long-lasting changes in neuroendocrine systems as well as lasting changes in behavior. The present study examines the long-term consequences of daily periods of social isolation during the third postnatal week on radial arm maze performance in adulthood. Male rat pups were either isolated for 6 h per day between postnatal days 15-21 or remained in ...

Journal: :Acta pharmacologica Sinica 2003
Yu-Wen Huang Zhong Chen Wei-Wei Hu Li-San Zhang Wei Wu Li-Yang Ying Er-Qing Wei

AIM To investigate whether or not histamine is involved in spatial memory deficits induced by dizocilpine (MK-801) as evaluated by 8-arm radial maze of rats. METHODS 8-Arm (4-arm baited) radial maze was used to measure spatial memory in rats. RESULTS Bilaterally intrahippocampal (ih) injection of MK-801 (0.3 microg/site) impaired working memory and reference memory in rats. Both histamine (...

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