نتایج جستجو برای: quinine imine
تعداد نتایج: 5773 فیلتر نتایج به سال:
The activities of primaquine in combination with quinine or artesunate against asexual- and sexual-stage parasites were assessed in 176 adult Thai patients with uncomplicated Plasmodium falciparum malaria. Patients were randomized to one of the six following 7-day oral treatment regimens: (i) quinine alone, (ii) quinine with tetracycline, (iii) quinine with primaquine at 15 mg/day, (iv) quinine...
The microstructure of the licking behavior of water-deprived rats presented with either water or quinine during 45-min single-bottle tests was analyzed. The chorda tympani (CT) and glossopharyngeal (GL) nerves, which innervate the taste buds of the tongue, were transected in deeply anesthetized rats to discern their contribution to the behavioral pattern of quinine drinking. Rats were presurgic...
A 23-year-old woman experienced six distinct episodes of severe combined neutropenia and thrombocytopenia. At least one of the episodes was accompanied by hemodialysis-requiring acute renal failure and fragmentation hemolysis (hemolytic uremic syndrome [HUS]). In retrospect, all episodes were probably associated with the ingestion of quinine. Quinine-dependent antibodies to platelets, neutrophi...
Relational database management systems manages the tables with predefined indexes. In RDBMS indexes are created on the basis of attribute values. The Imine indexing scheme is used to index item sets in relational databases. The index creation is performed with out any constraints. IMine provides a complete representation of the original database. The Imine indexing scheme reduces the input/outp...
The title anilide-imine compound, C(24)H(26)N(2)O, features an intra-molecular N-H⋯N hydrogen bond involving the imine and anilide groups to generate an S(6) ring motif. The mol-ecule displays an E configuration about the imine C=N double bond, with the dihedral angle between the two benzene rings being 86.5°. The packing is stabilized by three different C-H⋯π inter-actions.
In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line treatment for severe malaria, and for treatment of malaria in the first trimester of pregnancy. Quinine has been shown to have frequent clinical failures, and yet the mechanisms of action and resistance have not been fully elucidated. However, resistance is l...
Novel hybrid material poly(imide-imine) has been prepared, which exhibits self-healing behavior and recyclability enabled by the dynamic imine bonds while retaining tunable excellent mechanical thermal properties of polyimide.
An assay was developed measuring the disruption of rosettes between Plasmodium falciparuminfected (trophozoites) and uninfected erythrocytes by the antimalarial drugs quinine, artemisinin mefloquine, primaquine, pyrimethamine, chloroquine and proguanil. At 4 hr incubation rosettes were disrupted by all the drugs in a dose dependent manner. Artemisinin and quinine were the most effective anti-ma...
Free imine imidazol-2-imine ligands with two different substitution patterns have been isolated for the first time and they were found to exist as an equilibrium mixture of geometric and mesomeric isomers. The relative ratios of these isomers are dependent on both the nature of the substituents and of the solvent. The synthesis of the titanium(IV) alkyl and arylimido complexes of these ligands ...
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