نتایج جستجو برای: quantitative protein
تعداد نتایج: 1511903 فیلتر نتایج به سال:
Background and Objectives: Little is known about the association between dietary protein intake and clinical manifestations in osteoarthritis (OA) patients. We aimed to determine the correlation between dietary protein intake and pain severity, functional status, and body composition indices in patients with knee OA. Materials and Methods: This cross-sectional study was performed on 220 OA pat...
The elucidation of cross-talk events between intersecting signaling pathways is one main challenge in biological research. The complexity of protein networks, composed of different pathways, requires novel strategies and techniques to reveal relevant interrelations. Here, we established a combinatorial RNAi strategy for systematic single, double, and triple knockdown, and we measured the residu...
We present a statistical mechanics formalism for theoretical description of the process of protein folding ↔ unfolding transition in water environment. The formalism is based on the construction of the partition function of a protein obeying two-stage-like folding kinetics. Using the statistical mechanics model of solvation of hydrophobic hydrocarbons we obtain the partition function of infinit...
We develop a theoretical approach to the protein-folding problem based on out-of-equilibrium stochastic dynamics. Within this framework, the computational difficulties related to the existence of large time scale gaps are removed, and simulating the entire reaction in atomistic details using existing computers becomes feasible. We discuss how to determine the most probable folding pathway, iden...
Lot of research has gone into understanding the composition and nature of proteins, still many things remain to be understood satisfactorily. It is now generally believed that amino acid sequences of proteins are not random, and thus the patterns of amino acids that we observe in the protein sequences are also non-random. In this study, we have attempted to decipher the nature of associations b...
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