Cost utility analysis is a method of cost-effectiveness analysis which provides results in terms of cost per quality-adjusted life-year (QALY). Cost utility for the multichannel cochlear implant was calculated using Ontario Health Utilities Index data from 229 Nucleus 22-channel implant users and 32 cochlear implant candidates awaiting surgery. The health utility of the implanted group was grea...

PURPOSE To evaluate the relative benefits and cost-effectiveness of treating iliac arterial occlusive disease with various interventions. MATERIALS AND METHODS Cost-effectiveness was analyzed in a hypothetical cohort of patients with intermittent claudication caused by an iliac arterial stenosis. Primary stent placement, percutaneous transluminal angioplasty (PTA), and PTA with selective sten...

PURPOSE To ascertain the extent to which ophthalmologic interventions have been evaluated in value-based medicine format. METHODS Retrospective literature review. Papers in the healthcare literature utilizing cost-utility analysis were reviewed by researchers at the Center for Value-Based Medicine, Flourtown, Pennsylvania. A literature review of papers addressing the cost-utility analysis of ...

BACKGROUND Microvascular free tissue transfer has become the main technique used for head and neck reconstruction. We assessed the cost-effectiveness of free flap reconstruction for head and neck defects after oncologic resection for squamous cell carcinoma (SCC). METHODS We developed a Markov model of the cost, quality of life, survival, and incremental cost-effectiveness of reconstruction w...

BACKGROUND Genotypic antiretroviral resistance testing (GRT) in HIV infection with drug resistant virus is recommended to optimize antiretroviral therapy, in particular in patients with virological failure. We estimated the clinical effect, cost and cost-effectiveness of using GRT as compared to expert opinion in patients with antiretroviral treatment failure. METHODS We developed a mathemati...

BACKGROUND Recommendations on current clinical guidelines are informed by limited economic evidence. AIMS A formal economic evaluation of three modalities of psychotherapy for patients with cluster B personality disorders. METHOD A probabilistic decision-analytic model to assess the cost-effectiveness of out-patient, day hospital and in-patient psychotherapy over 5 years in terms of cost pe...

BACKGROUND To facilitate the discussion on the increasing number of total hip replacements (THR) and their effectiveness, we apply a joint evaluation of hospital case costs and health outcomes at the patient level to enable comparative effectiveness research (CER) based on the preoperative health state. METHODS In 2012, 292 patients from a German orthopedic hospital participated in health sta...

BACKGROUND Cost utility analysis (CUA) using SF-36/SF-12 data has been facilitated by the development of several preference-based algorithms. The purpose of this study was to illustrate how decision-making could be affected by the choice of preference-based algorithms for the SF-36 and SF-12, and provide some guidance on selecting an appropriate algorithm. METHODS Two sets of data were used: ...

Accelerated population aging has led to a progressive increase in dementia, particularly Alzheimer’s Disease (AD). The study’s objective was perform cost-utility analysis on the use of memantine severe stage AD Brazil compared no specific pharmacological treatment from perspective Brazilian Unified Health System (SUS). A Markov model designed simulate progression through five finite stages heal...

BACKGROUND The sustained health-related quality-of-life of patients surviving community-acquired pneumonia has not been accurately quantified. The aim of the current study was to quantify differences in health-related quality-of-life of community-dwelling elderly with and without community-acquired pneumonia during a 12-month follow-up period. METHODS In a matched cohort study design, nested ...