نتایج جستجو برای: qtl mapping

تعداد نتایج: 202966  

Journal: :G3: Genes, Genomes, Genetics 2021

Abstract Phenotypes of sessile organisms, such as plants, rely not only on their own genotypes but also those neighboring individuals. Previously, we incorporated neighbor effects into a single-marker regression using the Ising model ferromagnetism. However, little is known regarding how should be in quantitative trait locus (QTL) mapping. In this study, propose new method for interval QTL mapp...

2014
Il-Youp Kwak Candace R. Moore Edgar P. Spalding Karl W. Broman

Most statistical methods for quantitative trait loci (QTL) mapping focus on a single phenotype. However, multiple phenotypes are commonly measured, and recent technological advances have greatly simplified the automated acquisition of numerous phenotypes, including function-valued phenotypes, such as growth measured over time. While methods exist for QTL mapping with function-valued phenotypes,...

Journal: :Genetics 2006
Manuela Casasoli Jeremy Derory Caroline Morera-Dutrey Oliver Brendel Ilga Porth Jean-Marc Guehl Fiorella Villani Antoine Kremer

A comparative genetic and QTL mapping was performed between Quercus robur L. and Castanea sativa Mill., two major forest tree species belonging to the Fagaceae family. Oak EST-derived markers (STSs) were used to align the 12 linkage groups of the two species. Fifty-one and 45 STSs were mapped in oak and chestnut, respectively. These STSs, added to SSR markers previously mapped in both species, ...

Journal: :Behavior genetics 2004
Bojan Basrak Chris A J Klaassen Marian Beekman Nick G Martin Dorret I Boomsma

The standard variance components method for mapping quantitative trait loci is derived on the assumption of normality. Unsurprisingly, statistical tests based on this method do not perform so well if this assumption is not satisfied. We use the statistical concept of copulas to relax the assumption of normality and derive a test that can perform well under any distribution of the continuous tra...

Journal: :The Journal of heredity 2005
C Lee

A simulation study was performed to see whether selection affected quantitative trait loci (QTL) mapping. Populations under random selection, under selection among full-sib families, and under selection within a full-sib family were simulated each with heritability of 0.3, 0.5, and 0.7. They were analyzed with the marker spacing of 10 cM and 20 cM. The accuracy for QTL detection decreased for t...

Journal: :Genetics 2007
Frank Johannes

Existing methods for mapping quantitative trait loci (QTL) in time-to-failure experiments assume that the QTL effect is constant over the course of the study. This assumption may be violated when the gene(s) underlying the QTL are up- or downregulated on a biologically meaningful timescale. In such situations, models that assume a constant effect can fail to detect QTL in a whole-genome scan. T...

2015
Sixin Liu Roger L. Vallejo Yniv Palti Guangtu Gao David P. Marancik Alvaro G. Hernandez Gregory D. Wiens

Bacterial cold water disease (BCWD) is one of the frequent causes of elevated mortality in salmonid aquaculture. Previously, we identified and validated microsatellites on chromosome Omy19 associated with QTL (quantitative trait loci) for BCWD resistance and spleen size in rainbow trout. Recently, SNPs (single nucleotide polymorphism) have become the markers of choice for genetic analyses in ra...

2016
Grace Lin Elaine Chua Laszlo Orban Gen Hua Yue

In aquaculture, growth and sex are economically important traits. To accelerate genetic improvement in increasing growth in salt-tolerant tilapia, we conducted QTL mapping for growth traits and sex with an F2 family, including 522 offspring and two parents. We used 144 polymorphic microsatellites evenly covering the genome of tilapia to genotype the family. QTL analyses were carried out using i...

2013
Xiaonan Li Nirala Ramchiary Vignesh Dhandapani Su Ryun Choi Yoonkang Hur Ill-Sup Nou Moo Kyoung Yoon Yong Pyo Lim

Brassica rapa is an important crop species that produces vegetables, oilseed, and fodder. Although many studies reported quantitative trait loci (QTL) mapping, the genes governing most of its economically important traits are still unknown. In this study, we report QTL mapping for morphological and yield component traits in B. rapa and comparative map alignment between B. rapa, B. napus, B. jun...

Journal: :PLoS ONE 2009
Sureshkumar Balasubramanian Christopher Schwartz Anandita Singh Norman Warthmann Min Chul Kim Julin N. Maloof Olivier Loudet Gabriel T. Trainer Tsegaye Dabi Justin O. Borevitz Joanne Chory Detlef Weigel

BACKGROUND Even when phenotypic differences are large between natural or domesticated strains, the underlying genetic basis is often complex, and causal genomic regions need to be identified by quantitative trait locus (QTL) mapping. Unfortunately, QTL positions typically have large confidence intervals, which can, for example, lead to one QTL being masked by another, when two closely linked lo...

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