The aim of this study was to determine the mechanism underlying the association between one-carbon metabolism and DNA methylation during chronic degenerative joint disorder, osteoarthritis (OA). Articular chondrocytes were isolated from human OA cartilage and normal cartilage biopsied, and the degree of cartilage degradation was determined by safranin O staining. We found that the expression le...

BACKGROUND Severe Clostridium difficile toxin-induced enteritis is characterized by exuberant intestinal tissue inflammation, epithelial disruption and diarrhea. Adenosine, through its action on the adenosine A2A receptor, prevents neutrophillic adhesion and oxidative burst and inhibits inflammatory cytokine production. Alanyl-glutamine enhances intestinal mucosal repair and decreases apoptosis...

Helicobacter pylori (H. pylori) infections are strongly implicated in human gastric mucosa–associated diseases. Forkhead box M1 (FoxM1), a key positive regulator of cell proliferation, is overexpressed in gastric cancer. MicroRNAs are important post-transcriptional regulators of gene expression. In this study, the effects of H. pylori infection on FoxM1 expression and possible mechanisms of car...

S. Bartkevičius Department of Theoretical Electric Engineering, Kaunas University of Technology, Studentų 48, 51367 Kaunas, Lithuania; ph +370 37 300253. E-mail., [email protected]. V. Bagdonas, M. Juraška, K. Šarkauskas Department of Control Engineering, Kaunas University of Technology, Studentų 48, 51367 Kaunas, Lithuania; ph +370 37 300290. E-mail, [email protected], min...

September 2019 onwards, New Delhi put several political leaders from Jammu to house arrest and imposed a statewide curfew that endured the August of February 2021. The number those detained exceeded 400 as center crackdown on opposition they labelled separatists. Why did have detain so many politicians activists? centre impose such long state which costed its economy 1.5 billion US dollars? Wha...

OBJECTIVE After initial treatment with total thyroidectomy and radioiodine ablation, most follow-up protocols for patients with differentiated thyroid carcinoma contain cyclic diagnostic I-131 imaging and serum thyroglobulin measurements. The applied diagnostic I-131 doses vary between 37 and 370 MBq. The aim of this study was to determine the yield of a diagnostic scan with 370 MBq I-131 in pa...

Both photosystems, PS 370 and PS 565, controlling behavioral responses in Halobacterium halobium [E. Hildebrand and N. Dencher, Nature 2 5 7 ,4 6 — 48 (1975)] are reversibly inhibited when bacteria are grown in the presence o f 1 m M nicotine which is known to block biosynthesis o f reti­ nal. Photobehavior can be restored within some minutes to hours by adding retinal to nicotinetreated bacter...