Cognitive assessment typically involves assessing a person’s cognitive performance in unfamiliar and arguably unnatural clinical surroundings. User-centred approaches to assessment and monitoring, driven by issues such as enjoyability and familiarity, are largely absent. Everyday technologies, for example, smartphones represent an opportunity to obtain an objective assessment of a person’s cogn...

To obtain high-performance Al-Si-based cast alloys, refinement and modification of Si phases are required. An Al-12Si/ZnS powder inoculant was designed fabricated using a chemical bath deposition method. The efficiency the for modifying eutectic phase in as-cast Al-12Si alloy studied. Results show that can significantly refine Al-Si alloys. best effect is achieved with 17.5wt.% powder. Coarse l...

The soluble fraction from rabbit brain was adsorbed on a column of phenyl-Sepharose. By applying a linear gradient with decreasing salt concentration and increasing pH, it was possible to separate calpain I and calpain II from each other and from the endogenous inhibitor calpastatin. Both enzymes were capable of degrading endogenously labelled neuronal proteins, including slowly axonally transp...

A disentanglement puzzle consists of mechanically interlinked pieces, and the puzzle is solved by disentangling one piece from another set of pieces. A string puzzle consists of strings entangled with one or more wooden pieces. We consider the generalized string puzzle problem whose input is the layout of strings and a wooden board with holes embedded in the 3-dimensional Euclidean space. We pr...

Gary Ostertag (Philos Stud 146:249–267, 2009) has presented a new puzzle for Russellianism about belief reports. He argues that Russellians do not have the resources to solve this puzzle in terms of pragmatic phenomena. I argue to the contrary that the puzzle can be solved according to Nathan Salmon’s (Frege’s puzzle, 1986) pragmatic account of belief reports, provided that the account is prope...

Three types of intelligent puzzle, a three-dimensional Escher puzzle (3DES), a 3D jigsaw puzzle (3DJG) and a color matching cubocatahedron puzzle (CUB), are developed by layer manufacturing. Each puzzle contains a common packing problem. Furthermore, there exist two important mechanisms, the rotation of CUB and the translation of 3DJG. 3DES is obtained on the basis of periodic arrangement of ic...

We address the new problem of puzzle layout as a new application of graph drawing. We present two abstract models of puzzles, permutation puzzles and cyclic puzzles, which can be modeled as puzzle graphs. Based on these models, we implement two puzzle generators and produce various layouts of the puzzles using graph drawing algorithms. Using these puzzle generators we can create new puzzles. Fu...