We present a modular tool chain for high performance CFD simulations of pulsatile blood flow in intracranial aneurysms. We describe a path from in-situ imaging (ie. CT and MRI) to flow simulations and show different modules for obtaining anatomically accurate and allover smooth meshes suitable for computed fluid dynamics (CFD) as well as methods for computing the blood flow in a robust and high...

INTRODUCTION In clinical practice, extracorporeal circulation (ECC) is normally performed with non-pulsatile flow by means of centrifugal or roller pumps, which makes it rather non-physiological for patients [1-3]. Currently used circuits are quite voluminous, characterized by large priming volumes and by extended blood contact with foreign surfaces. We have previously proposed an innovative EC...

The effect of pulsatile pulmonary flow after the modified Fontan procedure was examined in a model that simulated the right heart. An inlet overflow tank (preload), axial pulsatile pump, Wind-Kessel model (afterload), and an outlet overflow tank were connected in series. The standard conditions were flow 2.00 l/min with 12 mm Hg preload pressure, 3.0 Wood units resistance, and an outlet overflo...

An in-vitro flow study was conducted in a mildly atherosclerotic main coronary artery casting of man using sugar-water solutions simulating blood viscosity. Steady flow results indicated substantial increases in pressure drop, and thus flow resistance at the same Reynolds number, above those for Poiseuille flow by 30 to 100 percent in the physiological Reynolds number range from about 100 to 40...

BACKGROUND Published studies of the past decades have established that mass transfer across the dialyzer membrane is governed by diffusion, convection and osmosis. While the former is independent of the pressure in the liquids, the latter two are pressure dependent and are enhanced when the pressure difference across the membrane is increased. The goal of the present study is to examine the imp...

To study the hydrodynamics of the arterial system a knowledge of the elastic constants of the arterial wall, from which one can predict the ‘natural’ velocity, is of fundamental importance (Mc Donald, 1974).The aim of the present study is to analyze the effect of non-Newtonian nature of blood through an Elastic artery. The artery is considered elastic and blood is considered under power-law mod...

Wall shear stress (WSS) plays an important role in the formation, growth, and rupture of atherosclerotic plaques arteries. This study measured WSS diseased carotid artery phantoms with degrees stenosis varying from 0 to 60% both steady pulsatile flow. Experiments were performed using silico real flow phantoms. Blood velocities estimated plane wave (PW) vector Doppler. was then velocity gradient...

PURPOSE To evaluate choroidal blood flow changes in eyes with high myopia according to the pulsatile components of ocular blood flow analysis. METHODS A total of 104 subjects (52 males and 52 females) were included in this study. One eye of each participant was randomly selected and assigned to one of four refractive groups, designated as, hyperopes (n = 20; refractive error, ≥+1.00 diopter [...

INTRODUCTION The aim of the study was to determine the correlation between pulsatile ocular blood flow (POBF) and sleep apnoea syndrome (SAS). MATERIAL AND METHODS Patients were recruited from those who underwent polysomnography in the "Sleep Unit" of the physiology department (Medical University, Lodz, Poland). A total of 52 Caucasian patients, 34 with SAS and 18 age- and gender-matched cont...

BACKGROUND AND OBJECTIVE In endodontics, a major diagnostic challenge is the accurate assessment of pulp status. In this study, we designed and characterized a fiber-based laser speckle imaging system to study pulsatile blood flow in the tooth. STUDY DESIGN/MATERIALS AND METHODS To take transilluminated laser speckle images of the teeth, we built a custom fiber-based probe. To assess our abil...