OBJECTIVE To investigate the spectrum of pulmonary atresia and critical pulmonary stenosis using right ventricular outflow tract angiography and explore its implications for catheter interventional treatment. DESIGN Prospective clinical study. SETTING Two paediatric cardiology centres. SUBJECTS 11 neonates or infants (aged 1 day to 8 months; weighing 2.3 to 7.8 kg) with pulmonary atresia ...

We describe the case of a newborn with 22q11 deletion and an unusual form of common arterial trunk with the main pulmonary artery arising anteriorly at the level of the common arterial valve sinus. Case reports: We report the case of a term newborn male who presented to our institution with a prenatal diagnosis of congenital heart disease. His mother was a 29-year-old woman with 22q11 deletion ...

Aims: The purpose of this study was to determine whether there is any association between the optimal increase in mitral valve area and mitral transvalvular gradient decrement and pulmonary arterial pressure decrement after balloon mitral valvuloplasty (BMV) in patients with mitral stenosis. Methods: The study population consisted of 49 patients (47 women, 2 men; mean age = 43.7±13.35 years) wi...

We describe a 73 year-old patient with mitral valve pericardial bioprosthesis Carpentier-Edwards 29M implanted due to the rheumatic mitral stenosis 21 years ago. Hemodynamic destabilisation had emerged 18 months before the admission. Echocardiography revealed significant bioprosthesis degeneration with calcification of its leaflets, small pannus on the bioprosthetic ring, moderate mitral stenos...

Seven patients with mild to moderate pulmonic stenosis with intact ventricular septum were subjected to cardiac catheterization before and from 4 to 18 months after pulmonary valvulotomy. Despite uniform clinical improvement, remarkably slight changes were observed, following surgery, in right ventricular pressure, pulmonary artery pressure, pulmonary artery flow, and pulmonary valve area, when...

Congenital pulmonary valve stenosis has been associated with the development of massive pulmonary arterial (PA) dilatation. Over time, this dilatation may distort surrounding structures and lead to compression of the left main coronary artery (LMCA) or the left mainstem bronchus. In this report, we describe a patient with a history of chronic thromboembolic pulmonary hypertension (CTEPH) and co...

The majority of congenital heart defects (CHDs) occur as isolated malformations, while approximately 25-30% of them are associated with extracardiac anomalies, in the setting of large or submicroscopic chromosomal anomalies, mendelian disorders, and malformation associations. Some types of CHD, such as atrioventricular canal defect and interrupted aortic arch, are more frequently found in assoc...

The clinical course of 38 patients with congenital mitral stenosis (MS) is reviewed. Associated cardiac defects were present in 28 patients, including tetralogy of Fallot in five. In all but one of the eight patients with supravalvar mitral ring (SVR), there were concomitant abnormalities of the mitral valve. Delay in the diagnosis of MS was common. Serial cardiac catheterizations and pulmonary...

Uncorrected, long-term pulmonary regurgitation leads to right ventricular dilatation and dysfunction in a significant percentage of patients. We used magnetic resonance imaging (MRI) before and after surgery to assess the effect of pulmonary valve replacement with the Medtronic Freestyle bioprosthesis on right ventricular function and volume in nine patients with pulmonary regurgitation or sten...

Seven patients with mild to moderate pulmonic stenosis with intact ventricular septum were subjected to cardiac catheterization before and from 4 to 18 months after pulmonary valvulotomy. Despite uniform clinical improvement, remarkably slight changes were observed, following surgery, in right ventricular pressure, pulmonary artery pressure, pulmonary artery flow, and pulmonary valve area, when...