نتایج جستجو برای: ptm
تعداد نتایج: 1366 فیلتر نتایج به سال:
Lantibiotics are ribosomally synthesized peptide antibiotics composed of an N-terminal leader peptide that promotes the core peptide's interaction with the post translational modification (PTM) enzymes. Following PTMs, mutacin 1140 is transported out of the cell and the leader peptide is cleaved to yield the antibacterial peptide. Mutacin 1140 leader peptide is structurally unique compared to o...
Individual posttranslational modifications (PTMs) of p53 mediate diverse p53-dependent responses; however, much less is known about the combinatorial action of adjacent modifications. Here, we describe crosstalk between the early DNA damage response mark p53K382me2 and the surrounding PTMs that modulate binding of p53 cofactors, including 53BP1 and p300. The 1.8 Å resolution crystal structure o...
the potato tuber moth (ptm), phthorimaea operculella (zeller) is one of the important pests of potato in tropical regions. in this research, the toxicity of two insecticides, abamectin and deltamethrin on p. operculella was studied at 26 ± 1 c°, 65 ± 5% rh and photoperiod of 16:8 h (l: d). the concentrations were determined by preliminary dose setting experiments. distilled water was used as co...
سیب از جمله محصولات باغی صادراتی به شمار می‌آید که از جایگاه بالایی در زمینه اشتغال‌زایی و ارزآوری برخوردار است. در مطالعه حاضر، به تجزیه و تحلیل تجربی عمده بازارهای صادراتی سیب ایران با رهیافت رفتار قیمت‌گذاری برای بازار (PTM)، تحت شرایط دو نرخ ارزهای اسمی و واقعی پرداخته شد. در این راستا از داده‌های سالانه 1372 تا 1394 استفاده گردید. تجزیه و تحلیل اقتصاد سنجی با استفاده از مدل پانل تصحیح خطای...
Phage display has been used as a high-throughput platform for identifying proteins or peptides with desired binding or catalytic activities from a complex proteome. Recently, phage display has been applied to profile the catalytic activities of posttranslational modification (PTM) enzymes. Here, we highlight recent work elucidating the downstream targets of PTM enzymes by phage display, includi...
Persistent Turing machines (PTMs) are multitape machines with a persistent worktape preserved between successive interactions. They are a minimal extension of Turing machines (TMs) that express interactive behavior. Their behavior is characterized by input-output streams; PTM equivalence and expressiveness are defined relative to its behavior. Four different models of PTM behavior are examined:...
Vulnerability identification is crucial for cyber security in the software-related industry. Early methods require significant manual efforts crafting features or annotating vulnerable code. Although recent pre-trained models alleviate this issue, they overlook multiple rich structural information contained code itself. In paper, we propose a novel Multi-View Pre-Trained Model (MV-PTM) that enc...
Ubiquitylation is a versatile post-translational modification (PTM). The diversity of ubiquitylation topologies, which encompasses different chain lengths and linkages, underlies its widespread cellular roles. Here, we show that endogenous ubiquitin is acetylated at lysine (K)-6 (AcK6) or K48. Acetylated ubiquitin does not affect substrate monoubiquitylation, but inhibits K11-, K48-, and K63-li...
Potato tuber moth (PTM), Phthorimaea operculella, is a serious pest of stored potato in most countries where potatoes are grown. Entomopathogens offer promise as alternatives to broad spectrum insecticides for management of this pest. The fungus Muscodor albus, which produces a mixture of antimicrobial volatile organic chemicals, was tested for its insecticidal activity against PTM. Adults and ...
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