نتایج جستجو برای: ptk

تعداد نتایج: 1449  

2014
Xiang Li Junwei Zhang Hehu Tang Zhen Lu Shizheng Chen Yi Hong

BACKGROUND Surgical treatment modalities for post-traumatic kyphosis (PTK) remain controversial. Like vertebral column resection, closing-opening wedge osteotomy (COWO) can achieve satisfactory results for kyphosis with multiple etiologies. However, few studies have assessed this procedure for PTK. Our purpose was to evaluate the radiographic and clinical outcomes of COWO in a selected series o...

Journal: :Blood 2005
Ksenia Bagrintseva Stefanie Geisenhof Ruth Kern Sabine Eichenlaub Carola Reindl Joachim W Ellwart Wolfgang Hiddemann Karsten Spiekermann

FLT3 (fms-like tyrosine kinase 3) is constitutively activated in about 30% of patients with acute myeloid leukemia (AML) and represents a disease-specific molecular marker. Although FLT3-LM (length mutation) and TKD (tyrosine kinase domain) mutations have been considered to be mutually exclusive, 1% to 2% of patients carry both mutations. However, the functional and clinical significance of thi...

Journal: :American journal of physiology. Renal physiology 2002
Dao-Hong Lin Hyacinth Sterling Kenneth M Lerea Paul Welling Lianhong Jin Gerhard Giebisch Wen-Hui Wang

We purified His-tagged ROMK1 and carried out in vitro phosphorylation assays with (32)P-radiolabeled ATP to determine whether ROMK1 protein is a substrate for PTK. Addition of active c-Src and [(32)P]ATP to the purified ROMK1 protein resulted in the phosphorylation of the ROMK1 protein. However, c-Src did not phosphorylate R1Y337A in which tyrosine residue 337 was mutated to alanine. Furthermor...

Journal: :Arquivos brasileiros de oftalmologia 2016
Erdem Yuksel Mehmet Ozgur Cubuk Hulya Yazıcı Eroglu Kamil Bilgihan

PURPOSE To evaluate the visual outcomes, recurrence patterns, safety, and efficacy of excimer laser phototherapeutic keratectomy (PTK) in conjunction with mitomycin C (MMC) for corneal macular and granular diystrophies. METHODS The patients were divided into two groups. Group 1 included patients with macular corneal dystrophy (MCD) that caused superficial corneal plaque opacities, and Group 2...

2008
Dario V. Forte Angelo Cavallini Cristiano Maruti Luca Losio Thomas Orlandi Michele Zambelli

PTK is a new open-source tool for all complex digital investigations. It represents an alternative to the well-known but now obsolete front-end Autopsy Forensic Browser. This latter tool has a number of inadequacies taking the form of a cumbersome user interface, complicated case and evidence management, and a non-interactive timeline that is difficult to consult. A number of important function...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2003
John Ross William M Armstead

Previously, superoxide (O2 -) has been observed to impair pial artery dilation (PAD) to activators of the ATP-sensitive (KATP) and calcium-sensitive (KCa) K+ channels. This study tested the hypothesis that activation of protein tyrosine kinase (PTK) and the ERK isoform of MAPK by O2 - contribute to impairment of KATP and KCa channel PAD. Exposure of the cerebral cortex to a xanthine oxidase O2 ...

2002
Arik Dvir Yoram Milner Alexander Levitzki David Inez Myers

Protein tyrosine kinase blockers of the tyrphostin family inhibited the EGF-dependent proliferation of human and guinea pig keratinocytes grown in culture and induced their growth arrest. These blockers also significantly inhibited the growth of epidermal keratinocytes, but not of dermal cells, in whole skin organ culture from both guinea pig and human origin. The antiproliferative activity of ...

2015
George D Kymionis Michael A Grentzelos Nektarios E Klados Niki A Xanthopoulou Theodore A Paraskevopoulos Efstathios T Detorakis

PURPOSE To report a corneal collagen cross-linking (CXL) mushroom shape demarcation line profile after limited Bowman's membrane removal by phototherapeutic keratectomy (PTK). METHODS Case report. RESULTS A twenty-one-year-old male with progressive keratoconus underwent mechanical epithelial debridement (at an 8.5 mm zone) followed by PTK (at a 5.0 mm zone and in a 10 μm depth) and CXL. No ...

2000
Y Marunaka N Niisato Y Ito

1) A beta agonist stimulated Na+ transport and decreased the intracellular Cl concentration ([Cl]c) associated with cell shrinkage via an increase in cytosolic cAMP level by activating adenylate cyclase in rat fetal distal lung epithelial (FDLE) cells. 2) Lowering [Cl-]c activated a 28-pS nonselective cation (NSC) channel by elongating the open time of the channel. 3) cAMP signals were converte...

Journal: :Archivos de la Sociedad Espanola de Oftalmologia 2012
M Ibarz Barberá M García González M Teus Guezala

OBJECTIVE To describe the use of transepithelial phototherapeutic keratecomy for the long-term treatment of post-laser in situ keratomileusis (LASIK) flap macrostriae. METHOD We present the case of a 22 year old male with visual loss in the left eye due to chronic flap macrostriae that was treated with transepithelial PTK. RESULTS Striae and haze were no longer visible, with a significant i...

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