Recent studies indicated an important role of the monoaminergic nervous systems (dopaminergic, noradrenergic, and serotonergic systems) and stress in the regulation of cytochrome P450 (CYP) expression and activity in the liver. The aim of our present research was to determine the effect of the novel atypical neuroleptic drug with antidepressant properties lurasidone, on the expression (mRNA and...

Although data are inconclusive, popular perception has linked military combat, posttraumatic stress disorder (PTSD), and criminal behavior. This paper discusses the multifactorial elements of this association that include both conscious and unconscious parameters of psychologic functioning. Testimony on combat-related PTSD has been presented in the courtroom to support veterans' claims of not g...

Art, dance, and music therapy are a significant part of complementary medicine in the twenty-first century. These creative arts therapies contribute to all areas of health care and are present in treatments for most psychologic and physiologic illnesses. Although the current body of solid research is small compared with that of more traditional medical specialties, the arts therapies are now va...

The effect of hypnotic suggestion of naturally occurring and experimentally induced psychologic stress on the respiratory system was studied in 11 young male subjects. It was found that hypnotic suggestion of deep relaxation and depression formed one end of the spectrum, while suggestion of exercise, anger, and anxiety formed the other end. Patterns of response in the first group were called no...

Volume kinetics is a method used for analyzing and simulating the distribution and elimination of infusion fluids. Approximately 50 studies describe the disposition of 0.9% saline, acetated and lactated Ringer's solution, based on repeated measurements of the hemoglobin concentration and (sometimes) the urinary excretion. The slow distribution to the peripheral compartment results in a 50-75% l...

Bruxism is a destructive habit that is defined as the nonproductive diurnal or nocturnal clenching or grinding of the teeth. This study investigated whether the combination of physical abnormalities, type A behavior pattern, and the perceived desirability and controllability of life stress are related to bruxism. The subjects for the study were 125 dental patients who were classified as bruxers...

Although expectation has been the most widely studied of the mechanisms that drive the placebo effect, we still don't know how it works. We don't know how the thought that one will respond to a substance in a certain way is converted to symptom relief, intoxication, or airway resistance; the pathway between expectation of a response and the response itself remains uncharted. Nonetheless, in the...