This study proposed a drug delivery system based on a series of formulations with chitosan gels, designed for local, intra-pocket treatment of periodontal disease, containing two drugs (an antibiotic and a chimiotherapeutic-antimicrobian agent: tetracycline hydrochloride (T) and metronidazole benzoate (M), respectively. The formulations varied from the chitosan concentration (3-4%), and the dru...

Functional properties were identified for the total globulin (TG), 7S and 11S fractions of Lima bean (Phaseolus lunatus L.) seeds. The 11S component accounted for 58.3% of TGs and the 7S for 41.7%. Solubility was higher in the 7S fraction, especially at alkaline pHs. Water-holding capacity was similar (3 g water/g sample) in both globulin fractions. Oil-holding capacity was higher in the 11S fr...

Thermoplastic vulcanizates (TPVs) are a special class of thermoplastic elastomers, which are produced by simultaneously mixing and crosslinking a rubber with a thermoplastic polymer at an elevated temperature. Peroxide-cured TPVs based on blends of silicone rubber and thermoplastic Engage of two different types, mainly ethylene-octene and ethylenebutene copolymers at different blend ratios have...

the aim of this study was to investigate the rheological behavior and mucoadhesive nature of saliva substitutes, by incorporating various mucoadhesive polymers into an artificial saliva pump spray formulation. for this purpose various mucoadhesive polymers including cellulosic polymers in the range of 0.1-1.0% and carbomers such as c974p, c971, c934p and c971 in the range of 0.01-0.1% were adde...

Background and objectives: The purpose of this study was optimization of semisolid topical formulation from ethanol extract of turmeric and evaluation of rheological characterization and investigation of physicochemical control tests. Methods: The ethanolic extract was prepared with Soxhlet method and the compounds were isolated with silica gel column chromatog...

Background: Natamycin belongs to a large group of naturally occurring polyene antifungal antibiotics derived from Streptomyces natalensis. has restrictive pharmaceutical role because its extremely low aqueous solubility, which severely reduces the bioavailability drug. To improve absorption drug, nanocrystals natamycin were prepared and incorporated into in situ gel.
 Aim: solubility by pr...

Abstract Mixing and homogenization in anaerobic digesters are affected by the flow curve of sludge. The aim this study is to mathematically express dense anaerobically digested sludge behaving as thixotropic pseudoplastic fluids. Time-dependent changes two parameters, i.e., consistency index ( µ p ) n ), shear modeled using a second-order kinetic equation with coefficient that includes power fu...