نتایج جستجو برای: pseudomonsa aeruginosa

تعداد نتایج: 32809  

2015
Shaymaa Hassan Abdel-Rhman Areej Mostafa El-Mahdy Mohammed El-Mowafy

Mixed-species biofilms could create a protected environment that allows for survival to external antimicrobials and allows different bacterial-fungal interactions. Pseudomonas aeruginosa-Candida albicans coexistence is an example for such mixed-species community. Numerous reports demonstrated how P. aeruginosa or its metabolites could influence the growth, morphogenesis, and virulence of C. alb...

Journal: :Journal of immunology 2008
Tim O Hirche Rym Benabid Gaetan Deslee Sophie Gangloff Samuel Achilefu Moncef Guenounou François Lebargy Robert E Hancock Azzaq Belaaouaj

According to the widely accepted view, neutrophil elastase (NE), a neutrophil-specific serine protease, is a major contributor to Pseudomonas aeruginosa infection-associated host tissue inflammation and damage, which in severe cases can lead to death. Herein, we provide for the first time compelling evidence that the host rather employs NE to protect itself against P. aeruginosa infection. Usin...

خرم روز, سجاد, راهبری, نسیم, ربانی, سید محمدرضا, شریفی, اصغر, غریب پور, فرزانه, مرعشی فرد, مسعود, ملک حسینی, سیدعلی اصغر, پرهیزگاری, نجمه, یزدان پناه, محبوبه,

Background and Objective: Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial burn infections. Disease results from the production of numerous virulence factors, some of which are injected directly into the eukaryotic host cells via the type III secretion system (T3SS).The aim of this study was to determine the prevalence of cytotoxins encoding exoT, exoY, exoS and exoU genes...

2017
Yi Dou Jingning Huan Feng Guo Zengding Zhou Yan Shi

Objective To assess the application of antibacterial agents, alongside pathogen prevalence and Pseudomonas aeruginosa drug resistance, with the aim of understanding the impact of inappropriate antibacterial use. Methods This retrospective study assessed bacteria from wounds, catheters, blood, faeces, urine and sputum of hospitalized patients in burn wards between 2007 and 2014. The intensity of...

Journal: :Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2013
Deirdre Keating Mary J Crowe Barry Kennedy Abigail Salmon David Britton Charles G Gallagher Edward F McKone Kirsten Schaffer

BACKGROUND The identification of Pseudomonas aeruginosa (P. aeruginosa) isolates in sputum from cystic fibrosis (CF) patients can be challenging due to the multitude of phenotypic changes isolates undergo during adaptation to the microenvironment of the CF lung. METHODS We report the occurrence of shared P. aeruginosa isolates which failed identification by phenotypic methodologies and requir...

Journal: :The Journal of biological chemistry 2005
David W Zaas Mathew J Duncan Guojie Li Jo Rae Wright Soman N Abraham

Pseudomonas aeruginosa is a major cause of pneumonia in patients with cystic fibrosis and other immuncompromising conditions. Here we showed that P. aeruginosa invades type I pneumocytes via a lipid raft-mediated mechanism. P. aeruginosa invasion of rat primary type I-like pneumocytes as well as a murine lung epithelial cell line 12 (MLE-12) is inhibited by drugs that remove membrane cholestero...

2016
Darío Capasso María Victoria Pepe Jéssica Rossello Paola Lepanto Paula Arias Valentina Salzman Arlinet Kierbel

For opportunistic pathogens such as Pseudomonas aeruginosa, the mucosal barrier represents a formidable challenge. Infections develop only in patients with altered epithelial barriers. Here, we showed that P. aeruginosa interacts with a polarized epithelium, adhering almost exclusively at sites of multi-cellular junctions. In these sites, numerous bacteria attach to an extruded apoptotic cell o...

2010
Aufaugh Emam William G Carter Clifford Lingwood

Internalization of PAK strain Pseudomonas aeruginosa into human respiratory epithelial cell lines and HeLa cervical cancer cells in vitro was readily demonstrable via a gentamycin protection assay. Depletion of target cell glycosphingolipids (GSLs) using a glucosyl ceramide synthase inhibitor, P4, completely prevented P. aeruginosa internalization. In contrast, P4 treatment had no effect on the...

2016
Yan Li

Objective: To investigate infection distribution of Pseudomonas aeruginosa on burned patients in our hospital as well as its drug resistance in order to provide reference of clinical use of antibiotics. Methods: Statistically analysed 481 Pseudomonas aeruginosa and their drug sensitive test results from burned patients who were sent to hospital from January 2004 to December 2006. Results: In ou...

Journal: :Microbiology 1997
J M Meyer A Stintzi D De Vos P Cornelis R Tappe K Taraz H Budzikiewicz

Eighty-eight Pseudomonas aeruginosa isolates, most of them from the Collection of Bacterial Strains of the Institut Pasteur, Paris, were analysed for their pyoverdine-mediated iron incorporation system by different methods, including pyoverdine isoelectrofocusing analysis, pyoverdine-mediated growth stimulation, immunoblot detection of (ferri)pyoverdine outer-membrane receptor and pyoverdine-fa...

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