OBJECTIVES To assess whether the increased sensitivity of screening for human papillomavirus (HPV) may represent overdiagnosis and to compare the long term duration of protective effect against cervical intraepithelial neoplasia grade 2 or worse (CIN2+) in HPV based and cytology based screening. DESIGN 13 year follow-up of the Swedescreen randomised controlled trial of primary HPV screening. ...

background and objectives: alzheimer's disease (ad) as a neurodegenerative disorder is the most common form of dementia in the elderly. according to the amyloid hypothesis, accumulation of amyloid beta (aβ) plaques, which are mostly constituted of aβ peptide aggregates, triggers pathological cascades that lead to neuronal cell death. thus, modulation of aβ toxicity is the hopeful therapeut...

objective: liver is an important organ that is exposed to many oxidant and carcinogenic agents, thus antioxidant compounds are beneficial for liver health. artemisia contains flavonoid compounds and anti-diabetic, antioxidant, and anti-inflammatory properties. due to possessing terpene and sesquiterpene compounds, this plant has antioxidant properties. this study was done to investigate the eff...

skin cancer is the most prevalent type of cancer in most of the countries and more than 90% of cancer cases are related to ultra violet rays of the sun. therefore protective behaviors against sunlight are considered the most essential measures for skin cancer prevention. this study has been conducted to determine the frequency of protective behavior against sunlight among female students of teh...

conclusions tg showed protective effect against ethanol induced gastric ulcer. this study confirmed traditional medicine claims of tg. objectives the aim of the present study was to determine the acute toxicity and protective effect of hydroalcoholic extract of tg (hetg) against ethanol induced gastric ulcer. materials and methods male wistar rats were divided into five groups (n = 7). hetg at ...

 Abstract Background: Cervical cancer is the most common female genital tract malignancy and is the major cause of death from gynecologic cancer worldwide. The majority of cervical cancers develop through a series of gradual, precancerous lesions. Screening asymptomatic women with regular Pap smears allows diagnosis of the readily treatable preinvasive phase. We performed this study to determin...

The aim of this descriptive study was to compare the report profiles of Caucasian, Aboriginal, and other visible minority children whose cases were assessed by child protective services in Canada. The results show that children of Aboriginal ancestry and from visible minority groups are selected for investigation by child protective services 1.77 times more frequently than are children in the g...

Screening for colorectal cancer (CRC) using sigmoidoscopy or colonoscopy is now common in many developed countries. This concise, evidence-based review looks at the impact of sigmoidoscopy or colonoscopy screening on CRC incidence, CRC mortality and overall mortality. Data from controlled retrospective and prospective (observational or randomized) studies have generally shown that sigmoidoscopy...

OBJECTIVE To quantify the degree of abuse or criminal behavior among young females presenting for reproductive health care services. METHODS An evaluation was conducted among Alaskan females age 10 through 15 years enrolled in Medicaid. Subjects were identified who had experienced reproductive health outcomes. The Medicaid file was linked to a Child Protective Services database and a Juvenile...

This study examined rates of heavy drinking and alcohol problems in relation to drinking motives and protective behavioral strategies in university students with a documented current diagnosis of attention-deficit/hyperactivity disorder (ADHD; n = 31) compared with students with no history of ADHD (n = 146). Participants completed a Web-based questionnaire, and logistic regression models tested...