PURPOSE To assess the ability of multiparametric (mp) MRI (mp-MRI) to identify, stratify, and localize biopsy-proven prostate cancer lesions in a risk-stratified patient population. METHODS AND MATERIALS We retrospectively analyzed 57 patients who had mp-MRI and core needle biopsy during diagnostic prostate cancer evaluation. The MRI sequences were scored for suspicion of cancer with a previo...

An innovative fusion of previously acquired magnetic resonance imaging (MRI) images with real-time transrectal ultrasound (US) may lead to improved prostate cancer detection, thus necessitating fewer biopsies. Suspicious lesions can be identified, localised - and possibly classified - via an MRI scan. Subsequently, a biopsy needle can be guided accurately into the suspicious area of the prostat...

PURPOSE To compare and evaluate whether a 20 gauge (20G) biopsy needle maintains a similar detection rate as that of the commonly used 18G needle for transrectal ultrasound-guided prostate biopsy (TRUSPB) aimed at assessing prostate cancer (PCa) and decreasing pain and complications. MATERIALS AND METHODS A total of 122 cases with indications of PCa were randomly allocated into two groups for...

OBJECTIVE To evaluate safety and feasibility in a first-in-human trial of a direct magnetic resonance imaging (MRI)-guided prostate biopsy using a novel robotic device. METHODS MrBot is an MRI-safe robotic device constructed entirely with nonconductive, nonmetallic, and nonmagnetic materials and developed by our group. A safety and feasibility clinical trial was designed to assess the safety ...

Biopsies are one of the most common ways to diagnose and prognose prostate cancer. Transrectal Transperineal approaches used access for biopsy. Advancements in Magnet Resonance Imaging (MRI) offer a clear visualization soft tissues improved volumetric clarity. Real time MRI guidance can significantly change paradigm tissue Proposed is device with ability collect samples taken by biopsy needle d...

PURPOSE The pretherapeutic assessment of prostate cancer is challenging and still holds the risk of over- or undertreatment. This prospective trial investigates positron emission tomography (PET) with [(18)F]fluoroethylcholine (FEC) combined with endorectal magnetic resonance imaging (MRI) for the assessment of primary prostate cancer. EXPERIMENTAL DESIGN Patients with prostate cancer based o...

Background. The aim of this study was to determine concordance rates for prostatectomy specimens and transrectal needle biopsy samples in various areas of the prostate in order to assess diagnostic accuracy of the transrectal biopsy approach, especially for presurgical detection of cancer in the prostatic apex. Materials and Methods. From 2006 to 2011, 158 patients whose radical prostatectomy s...

to investigate and compare the infectious and non-infectious complications of single-dose versus multiple-dose antibiotic therapy for trans-rectal ultrasound (trus)-guided biopsy of the prostate. patients were enrolled in a prospective randomized study that was designed to investigate the effects of single-dose versus multiple-dose antimicrobial prophylaxis regimen mainly on asymptomatic bacter...

Prostate cancer is the second leading cause of cancer-related death among American men. Biopsy for prostate cancer is a procedure known as transrectal ultrasound-guided needle biopsy. Because of the low resolution of ultrasound, the urologist cannot usually distinguish between cancerous and healthy tissue. For this reason, most biopsies follow standard protocols based on long-term experience of...