OBJECTIVE To assess the patterns of chemotherapy use for patients with multiple myeloma and to determine if chemotherapy is effective in prolonging survival outside the clinical trial settings. METHODS We studied a nationwide and population-based retrospective cohort of 4902 patients > or =65 years of age with stage II or III multiple myeloma from 1992 to 1999, identified from the Surveillanc...

background: although the cox proportional hazard regression is the most popular model for analyzing the prognostic factors on survival of cancer patients, under certain circumstances, parametric models estimate the parameter more efficiently than the cox model.  the aim of this study was to compare the cox regression model  with parametric models in patients with gastric cancer who registered a...

In this paper, we discuss the prediction problem based on censored coherent system lifetime data when the system structure is known and the component lifetime follows the proportional reversed hazard model. Different point and interval predictors based on classical and Bayesian approaches are derived. A numerical example is presented to illustrate the prediction methods used in this paper. Mont...

Background Network meta-analysis (NMA) combines direct and indirect evidence from trials to calculate treatment effect estimates and rank treatments. Modelling approaches for continuous and binary outcomes are relatively well developed, but less work has been done with time-toevent outcomes. Such outcomes have usually been analysed using Cox proportional hazard (PH) models, but in oncology with...