The interaction during stimulation of cGMP and inhibition of cAMP was investigated in control and renal hypertensive hearts. Control and hypertensive [1 kidney, 1 clip (1K1C)] rabbits were used. The anesthetized open-chest groups were vehicle, 8-bromo-cGMP (8-Br-cGMP; 10(-3)M), propranolol (Prop; 2 mg/kg), and Prop + 8-Br-cGMP. O(2) consumption levels (Vo(2)) in the subepicardium (Epi) and sube...

Behavioral reaction to different taste qualities affects nutritional status and health. 6-n-Propylthiouracil (PROP) tasting has been reported to be a marker of variation in taste perception, food preferences, and eating behavior, but results have been inconsistent. We showed that l-Arg can enhance the bitterness intensity of PROP, whilst others have demonstrated a suppression of the bitterness ...

Detection thresholds and psychophysical curves were established for caffeine, quinine-HCl (QHCl), and propylthiouracil (PROP) in a sample of 33 subjects (28 female mean age 24 +/- 4). The mean detection threshold (+/-standard error) for caffeine, QHCl, and PROP was 1.2 +/- 0.12, 0.0083 +/- 0.001, and 0.088 +/- 0.07 mM, respectively. Pearson product-moment analysis revealed no significant correl...

Mutations in the prophet of Pit-1 (PROP-1) gene are responsible for most of the cases of combined pituitary hormone deficiencies (CPHD). We performed this study to determine the prevalence of PROP-1 mutations in a group of Turkish children with CPHD. Fifty-three children with the diagnosis of CPHD were included in this study. Clinical data were obtained from medical files, and hormonal evaluati...

Rodriguez, Roberto, Bruno Molino, Harvey R. Weiss, and Peter M. Scholz. Negative metabolic and coronary flow effects of decreases in cAMP and increases in cGMP in control and renal hypertensive rabbit hearts. J Appl Physiol 97: 439–445, 2004. First published February 27, 2004; 10.1152/japplphysiol.01115.2003.— The interaction during stimulation of cGMP and inhibition of cAMP was investigated in...

From Wright Brothers 1903 to present day 2003, aeronautical technology has made a profound progress. This paper demonstrates the outcome of this progress in weight, wing area, and engine thrust in three categories of transport aircraft of short to long range, regional jets, and turbo-prop commuter aircraft. Also the paper includes those aircraft with distinct jump in aeronautical technology. Fe...

We display three equivalent conditions for a sublattice, isomorphic to a ~ ( ~ ) , of the propositional system ~(JC) of a quantum system to be the representation of a physical subsystem (see [1 ] ). These conditions are valid for dim ~ ~> 3. We prove that one of them is still necessary and sufficient if dim ~ < 3. A physical interpretation of this condition is given. I N T R O D U C T I O N Wor...

BACKGROUND In response to increases in methamphatemine-associated sexually transmitted diseases, the San Francisco Department of Public Health implemented a contingency management (CM) field program called the Positive Reinforcement Opportunity Project (PROP). METHODS Methamphetamine-using men who have sex with men (MSM) in San Francisco qualified for PROP following expressed interest in the ...

BACKGROUND This study compared two types of sedation in pregnant women receiving subarachnoid anaesthesia for elective Caesarean section. METHODS This prospective randomised study included 56 women. Patients were sedated with propofol (PROP group, n = 27) or midazolam (MID group, n = 29) via intravenous infusion after extraction of the foetus. The following parameters were assessed at five-mi...