OBJECTIVE  The study was conducted to analyze the predictors of prolonged hospitalization in patients with fever. PATIENTS AND METHODS  This was a prospective cohort study conducted from July - December 2015 at Ayub Teaching Hospital, Pakistan. Convenience sampling was used to enroll the patients who visited the hospital during the study duration. A sample size of 115 patients was calculated....

conclusions subcutaneous nodules in the absence of a local reaction at the site of bcg vaccination may be the sole manifestation of disseminated bcg disease. case presentation we report on an 11-months-old boy with prolonged fever and diffuse hyperpigmented subcutaneous nodules. due to lymphopenia, oral thrush and severe adverse reaction to bcg vaccination, the possibility of primary immunodefi...

Fever of unknown origin has been described as a febrile illness (temperature of 101°F [38.3°C] or higher) for three weeks or longer without an etiology despite a one-week inpatient evaluation. A more recent qualitative definition requires only a reasonable diagnostic evaluation. Although there are more than 200 diseases in the differential diagnosis, most cases in adults are limited to several ...

CASE I A 70 year old woman presented with a pleural effusion containing undifferentiated carcinoma cells. Biopsy of an enlarged cervical gland yielded material with the histological features of adenocarcinoma. She had a previous history of systemic lupus erythematosus and seropositive arthritis. Corynebacterium parvum (7 mg in 20 ml normal saline) was instilled into the pleural cavity after asp...

OBJECTIVE To estimate the prevalence of connective tissue diseases in patients presenting with fever of unknown origin (FUO). PATIENTS AND METHODS In this study thirty patients diagnosed as FUO (Group 1), in 2008, were included in an observational study and diagnostic workup. Additionally, retrospective analysis of seventy patients' files (Group 2), for patients who presented with prolonged u...

Non typhoidal salmonellosis (NTS) is on the rise in many countries. Most common causes of NTS are Salmonella enterica serovars Typhimurium, Enterica, Newport and Heidelberg and typically present as self limiting gastroenteritis. However, in immunocompromised individuals and children, complications like bacteremia and focal metastatic infections can ensue. Antibiotic resistance is also of concer...

A case of prolonged thrombocytopenia following dengue haemorrhagic fever in a 15 year old boy is reported. The mechanism was presumed to be immunological and he responded dramatically to oral prednisolone.

BACKGROUND The majority of young children with fever and urinary tract infections (UTIs) have evidence of pyelonephritis based on renal scans. Resolution of fever during treatment is 1 clinical marker of adequate treatment. Theoretically, prolonged fever may be a clue to complications, such as urinary obstruction or renal abscess. OBJECTIVE Describe the pattern of fever in febrile children un...

We present a case of malignant fibrous histiocytoma accompanied by prolonged spiking fevers, which disappeared after tumor resection. Sarcoma with fever as a primary symptom is rare. Furthermore, in this case, fever was closely related to the clinical course of the tumor. In order to detect possible production of febriferous substance(s), we used blood and tumor tissue samples to investigate ni...

M e t h o d s Design: Randomized placebo-controlled trial. Allocation: {Concealed}†.* Blinding: Blinded {clinicians, patients, data collectors, outcome assessors, data analysts, and data safety and monitoring committee}†.* Follow-up period: Until resolution of neutropenia: median 15 to 19 days in patients with leukemia and 8 days in patients with solid tumors or lymphoma. Setting: 35 centers in...