Aim: to evaluate prognostic factors in colorectal cancer. Material and methods: published data (publications PubMed, Scopus, eLIBRARY databases) own results of treatment 47 patients with T2-4N0-2M0 colon cancer 2017–2018. The following were studied: metastasis regional lymph nodes, tumor site, CEA level, KRAS BRAF mutation status, microsatellite instability, MUSASHI2, p53, VEGF. Results: a corr...

background stroke is the second cause of death and disability in the world, and oxidative stress which could be considered as a prognostic factor in patients for prevention, follow up and determination of stroke’s severity has a conceivable role in neural damage. objectives the aim of our study was to explain the association between oxidant/antioxidant imbalance as a prognostic factor in patien...

background : the brain is a rare site of metastases from ovarian cancer. limited data are available on prognostic factors, standard treatment, and survival. knowledge of clinical prognostic factors would help the management of patients with brain metastases. the aim of this study is to evaluate the impact of clinical factors and treatment modalities on survival in patients with brain metastases...

Colorectal cancer is one of the most common malignancies, often presenting with a poor prognosis. To date, the anatomic extent of disease has been by far the most important prognostic factor. Recently, we obtained evidence that the type, density, and location of immune cells in colorectal cancer could provide a prognostic factor superior and independent to that of criteria related to the anatom...

Hand eczema extent was a strong negative prognostic factor in a previously published follow-up study of 868 individuals. The present aims were to study in the same cohort the association between the extent and the morphology of the hand eczema and to examine whether registering both improves the prediction of long-term prognosis. The cohort was divided into subgroups regarding eczema extent and...

Randomization is a hallmark of clinical trials. If a trial entails very few subjects and has many prognostic factors (or many factor levels) to be balanced, minimization is a more efficient method to achieve balance than a simple randomization. We propose a novel minimization method, the 'two-way minimization'. The method separately calculates the 'imbalance in the total numbers of subjects' an...

Background & Aim: Traumatic brain injury is one of the main causes of death and disability. The aim of this study is to systematically review the articles which assessed some serum factors of traumatic brain injury patients in relation to their outcomes. Methods & Materials/Patients: Databases were searched for relevant publications from 2005 to 2014. Selection criteria were:Studies which ev...

Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. Methods: In the current cr...