نتایج جستجو برای: procoagulant activity
تعداد نتایج: 1135551 فیلتر نتایج به سال:
BACKGROUND Septic shock-induced disseminated intravascular coagulation is responsible for increased occurrence of multiple organ dysfunction and mortality. Immunothrombosis-induced coagulopathy may contribute to hypercoagulability. We aimed at determining whether recombinant human thrombomodulin (rhTM) could control exaggerated immunothrombosis by studying procoagulant responses, fibrinolysis a...
Cancer is a leading cause of thrombosis. We identify a new procoagulant mechanism that contributes to thromboembolism in prostate cancer and allows for safe anticoagulation therapy development. Prostate cancer-mediated procoagulant activity was reduced in plasma in the absence of factor XII or its substrate of the intrinsic coagulation pathway factor XI. Prostate cancer cells and secreted prost...
Chronic lymphocytic leukaemia (CLL) is associated with a low incidence of thrombotic complications, or disseminated intravascular coagulation (DIC), or both, despite the frequent occurrence of severe infections. We have investigated the capacity of blood mononuclear cells to produce procoagulant activity when stimulated with bacterial endotoxin in 16 patients with untreated chronic lymphocytic ...
We report a case of Crohn’s disease (CD) presenting as thromboembolic middle cerebral artery stroke due to left ventricular (LV) thrombus in 50-year-old lady. The proinflammatory and procoagulant state reported CD seems responsible for this. patient was managed with conservative treatment, but she died quickly. findings highlight the rare occurrence LV well need aggressive control activity dise...
G RAEBER AND STUART’ reported an increase in procoagulant activity in the cerebrospinal fluid (CSF) of children with acute lymphoblastic leukemia (ALL) following prophylactic central ncrvous system (CNS) treatment with cranial radiation and intrathecal methotrexate. They postulated that the shortening of the plasma recalcification time (PRT) reflected the presence of brain phospholipid released...
Interleukin 1 (IL-1) is a potent mediator of inflammatory and immunologic phenomena. In addition, IL-1 may be intimately involved in the regulation of hemostasis, since interaction of IL-1 with endothelial cells has been reported to induce tissue factor activity. We demonstrate that perturbation of the endothelial cell induces augmented IL-1 release. Human umbilical vein endothelial cells pertu...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید