The waste associated with cleaning of process equipment is probably a significant contr ibutor to the total waste volume generated by industry. This paper addresses the following aspects related to equipment cleaning waste generation: o Review of reasons for cleaning process equipment o Reduction of cleaning frequency o Reduction of quantity and toxicity of cleaning waste o Costs associated wit...

Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...

Improving the use of power plant information sources for equipment fault diagnosis will help electric utilities meet plant availability goals and reduce operations and maintenance costs. The combination of data from multiple information sources--such as data historians, predictive maintenance technologies, and operator rounds-can provide a holistic view of condition for a given item of equipmen...

In this paper, it is proposed to develop the fault diagnosis system using the principal component analysis (PCA) for the intelligent operation support system that calculates the effect of fault propagation in abnormalities situation and gives appropriate information to plant operators. This proposed system using PCA discriminates a failure of equipment based on process variables. The proposed m...

Developing stable formulations is generally a common target to obtain efficacious emulsified vaccines. Process used to perform water in oil (W/O) emulsions are not all equivalent regarding vaccines physico-chemical parameters. Equipment generally used to realise emulsified vaccines can be high shear mixers, vortex, syringes, or syringes connectors. It was already reported that applied process h...

The emergence of the fourth industrial revolution was made possible by and rapid spread cyberphysical systems. One major developments this era digital twin model. is not just a 3D model or simple simulation. It can be used to create real-time observed physical element that collects environmental data using sensors also predict failure product based on information provided. If system has actuato...