This paper examines and ranks restoration alternatives for improving fish habitat by evaluating tradeoffs between fish production and restoration costs. Optimization modelling is used to maximize out‐migrating coho salmon (Oncorhynchus kisutch) from a natal stream and is applied as a case study in California’s Shasta River. Restoration activities that alter flow and water temperature conditions...

In clonal systems, interpreting driver genes in terms of molecular networks helps understanding how these drivers elicit an adaptive phenotype. Obtaining such a network-based understanding depends on the correct identification of driver genes. In clonal systems, independent evolved lines can acquire a similar adaptive phenotype by affecting the same molecular pathways, a phenomenon referred to ...

Business stakeholders need to have clear and realistic goals if they want to meet commitments in application development. As a consequence, at early stages they prioritize requirements. However, requirements do change. The effect of change forces the stakeholders to balance alternatives and reprioritize requirements accordingly. In this paper we discuss the problem of priorities to non-function...

The choice of how much money and resources to spend to understand certain problems is of high interest in many areas. This work illustrates how computational models can be more tightly coupled with experiments to generate decision data at lower cost without reducing the quality of the decision. Several different strategies are explored to illustrate the trade off between lowering costs and qual...