ABSTRACT: Quantitative structure-activity relationship (QSAR) study on the piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines as potent butyrylcholinestrase (BuChE) inhibitors were carried out using statistical methods, molecular dynamics and molecular docking simulation. QSAR methodologies, including classification and regression tree (CART), multiple linear regression (MLR),...

A method of face recognition based on multiscale principal component analysis (MSPCA) is presented in this paper. Initially face area is extracted from the given face image using Adaboost face detection algorithm. From the face area, regions of interest such as eyes, nose and mouth part are extracted by dividing it along horizontal and vertical directions. Then MSPCA is employed on these region...

Kernel Principal Component Analysis (KPCA) is a dimension reduction method that is closely related to Principal Component Analysis (PCA). This report gives an overview of kernel PCA and presents an implementation of the method in MATLAB. The implemented method is tested in a transductive setting on two data bases: Iris data and sugar data. Two methods for labeling data points are considered, th...

Principal Component Analysis (PCA) aims to learn compact and informative representations for data and has wide applications in machine learning, text mining and computer vision. Classical PCA based on a Gaussian noise model is fragile to noise of large magnitude. Laplace noise assumption based PCA methods cannot deal with dense noise effectively. In this paper, we propose Cauchy Principal Compo...

ABSTRACT Principal Component Analysis (PCA) is a basis transformation to diagonalize an estimate of the covariance matrix of input data and, the new coordinates in the Eigenvector basis are called principal components. Since Kernel PCA is just a PCA in feature space F , the projection of an image in input space can be reconstructed from its principal components in feature space. This enables us...

Principal Component Analysis (PCA) is often used for reducing the dimensionality of input feature space. However, the eigenspace based on PCA is not always the best feature space for pattern recognition. In this paper, we use the feature space based on Independent Component Analysis (ICA) and show that the ICA representation is more effective than the PCA representation for human action recogni...

Common factor analysis (CFA) and principal component analysis (PCA) are widely used multivariate techniques. Using simulations, we compared CFA with PCA loadings for distortions of a perfect cluster configuration. Results showed that nonzero PCA loadings were higher and more stable than nonzero CFA loadings. Compared to CFA loadings, PCA loadings correlated weakly with the true factor loadings ...

In this study, new and feasible UV-visible spectrophotometric and multivariate spectrophotometric methods were described for the simultaneous determination of hydrochlorothiazide (HCTZ), hydralazine hydrochloride (H.HCl), and reserpine (RES) in combined pharmaceutical tablets. Methanol was used as a solvent for analysis and the whole UV region was scanned from 200-400 nm. The resolution was obt...