Healthy carriers of severe Hemoglobinopathies are usually asymptomatic and only efficiently detected through screening campaigns. Based upon epidemiological data, screenings have been offered for decades to populations of endemic Southern Europe for primary prevention of Thalassemia Major, while for many populations of the highly endemic African and Asian countries prevention for Sickle Cell Di...

abstract background prevention of myocardial siderosis is a key step to reduce rate of mortality in thalassemic patients. our objective was to study association between echocardiography parameters and serum ferritin level in patients with major thalassemia. materials and methods sixty-six patients with major thalassemia were studied in amir kabir hospital, arak, iran. serum ferritin levels were...

Thalassemia is a group of inherited blood disorders due to the reduction or absence globin chain synthesis which can cause hemolytic anemia. β-thalassemia major severe type thalassemia, in patients require lifelong transfusions for survival. Extravascular hemolysis on spleen results splenomegaly, meanwhile, extramedullary hematopoiesis causing hypersplenism develop beta-thalassemia patients. Hy...

Abstract Background Prevention of myocardial siderosis is a key step to reduce rate of mortality in thalassemic patients. Our objective was to study association between echocardiography parameters and serum ferritin level in patients with major thalassemia. Materials and Methods Sixty-six patients with major thalassemia were studied in Amir Kabir hospital, Arak, Iran. Serum ferritin levels ...

Background: Thalassemia is the commonest hemoglobinopathy in our country of which β thalassemia most common. More and more endocrinological complications are seen current scenario children usually than 10 years age with significant iron overload due to inadequate chelation. Aim study understand common key factors for their prevention.Methods: A prospective analytical was done at a tertiary care...

Background Beta thalassemiais a genetic blood abnormality identified through mutations, which reduce the synthesis of the ß-globin chain. Gene therapy through Lentiviral vectors have cured many of genetic disorders. The purpose of this study was to investigate the efficacy of lentiviral vectors in treatment of ß-thalassemia a...

Abstract Background Thalassaemia, a hereditary haemoglobin disorder, is major public health concern in some parts of the world. Although Bangladesh world’s thalassaemia belt, information on this disease scarce. Additionally, awareness life threatening, but potentially preventable surprisingly poor. However, mass pivotal for development an effective preventive strategy. In context, understanding...

Background & Aims: Major ( -thalassemia is a chronic and costly disease for health care system. Although regular transfusion reduces the disease complications, it is associated with complications of hemosiderosis. This study was performed to determine ( – thalassemia complications in patients referred to Kerman center for special diseases regardless of their age. Methods: This cross-sectional s...

The recent transfer of Thalassemia Reports, the only journal fully dedicated on Thalassemia, from PagePress to MDPI was great news for those who contributed spread [...]