Case A baby girl was born via emergency lower segment caesarean section after 33 weeks’ gestation. The mother had developed premature uterine contraction, leaking liquor followed by acute fetal distress condition as shown on cardiotocograph. The 1.85 kg baby was intubated in the operating theatre because of respiratory distress. The baby was noted to have a fl at nasal bridge, low set ears, pro...

Defects in the surfactant biosynthesis are associated with respiratory distress syndrome, commonly occurring in premature infants due to lung immaturity. However, interstitial lung diseases have also been observed in full-term infants with mutations in the SFTPC, SFTPB, NKX2-1, or ABCA3 genes, involved in the surfactant metabolism. Herein, we report a newborn baby with neonatal respiratory dist...

INTRODUCTION We report the fi rst successful preimplantation genetic diagnosis (PGD) for Hb Bart's hydrops fetalis in Singapore, involving both fresh and frozen embryo replacement cycles. CLINICAL PICTURE Two couples who were carriers of the Southeast Asian type double gene deletion (--(SEA) deletion carriers) requested for PGD. Couple A had 2 previous affected pregnancies, while couple B hav...

Recent studies show that premature babies who need a supervision period can shorten this time if they are in a familiar environment. However, complications might arise at any time. This work proposes an approach to monitor babies at home. In this approach, baby sensors send data to a mobile device implementing an intelligent system that provides recommendations and supports the parents in the b...

practice. Occasionally intermediate cases have presented difficulty and some atypical examples, such as the case described by Nicholson and Claireaux (1948) which appeared to be a form of generalized infective cellulitis in an older baby, defy classification. A third condition, characterized by localized pitting oedema in cold premature babies, is sometimes called scleroedema but this is not al...

Herein reported is a case of congenital malignant melanoma in a premature male baby from a 25-year-old healthy mother who was found to have hydramnios at the 29th week of gestation. The pregnancy was interrupted because of a large posterior neck mass detected by ultrasonography. The large neck mass of the baby was a malignant melanoma involving deep dermis and subcutaneous tissue. The skin over...

BACKGROUND Little is known about how anxiety disorders affect pregnancy outcomes. Therefore we investigated the impact of one anxiety disorder, blood- and injection phobia, on obstetric and neonatal outcomes. METHODS From a population-based prospectively collected cohort we compared an index group of 110 women with blood- and injection phobia with a control group of 220 women. Standardized me...

AIM To observe how the resonance frequency changes with the course of respiratory distress syndrome (RDS), by examining the effect of changing static compliance on the resonance frequency in premature infants. METHODS In 12 ventilated premature infants with RDS (mean gestational age 26.6 weeks, mean birth weight 0.84 kg), resonance frequency and static compliance were determined serially usin...

BACKGROUND antenatal variant of Bartter syndrome is characterized by a history of polyhydramnios, premature birth, metabolic alkalosis, hypokalemia, polyuria and renal salt wasting. In this report we present a premature female baby with antenatal Barter syndrome who had three episodes of urinary tract infection (UTI), without evidence for congenital anomaly of the kidneys or urinary tract. ME...