نتایج جستجو برای: prelimbic

تعداد نتایج: 665  

Journal: :Learning & memory 2014
Elizabeth A Hinton Marina G Wheeler Shannon L Gourley

An important aspect of goal-directed action selection is differentiating between actions that are more or less likely to be reinforced. With repeated performance or psychostimulant exposure, however, actions can assume stimulus-elicited-or "habitual"-qualities that are resistant to change. We show that selective knockdown of prelimbic prefrontal cortical Brain-derived neurotrophic factor (Bdnf)...

2013
Michael T Stefanik Khaled Moussawi Yonatan M Kupchik Kyle C Smith Rachel L Miller Mary L Huff Karl Deisseroth Peter W Kalivas Ryan T LaLumiere

Inhibitory optogenetics was used to examine the roles of the prelimbic cortex (PL), the nucleus accumbens core (NAcore) and the PL projections to the NAcore in the reinstatement of cocaine seeking. Rats were microinjected into the PL or NAcore with an adeno-associated virus containing halorhodopsin or archaerhodopsin. After 12 days of cocaine self-administration, followed by extinction training...

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