نتایج جستجو برای: pregnant mice
تعداد نتایج: 456076 فیلتر نتایج به سال:
As a member of peroxiredoxin (Prx) family, PrxIII has been demonstrated to play an important role in scavenging intracellular reactive oxygen species (ROS). Since PrxIII knockout mice exhibited oxidative stress in placentas resembling pathophysiologic changes in placentas of human pre-eclampsia, we measured blood pressure through the carotid artery and detected oxidative status by Western blott...
Zika virus (ZIKV), a re-emerging flavivirus associated with neurological disorders, has spread rapidly to more than 70 countries and territories. However, no specific vaccines or antiviral drugs are currently available to prevent or treat ZIKV infection. Here we report that a synthetic peptide derived from the stem region of ZIKV envelope protein, designated Z2, potently inhibits infection of Z...
ZM is a plant used to remedy dyspepsias in pregnant women. EA is a plant used as a stomach and heart tonic, carminative and in remedy of skeletal and muscular ailments. In order to investigate the probable effects of this extracts on the fetus digestive system the current study was examind. Twenty-eight pregnant balb/c mice (25-30 gr) were divided into control, sham and expremental groups (n=7)...
ZM is a plant used to remedy dyspepsias in pregnant women. EA is a plant used as a stomach and heart tonic, carminative and in remedy of skeletal and muscular ailments. In order to investigate the probable effects of this extracts on the fetus digestive system the current study was examind. Twenty-eight pregnant balb/c mice (25-30 gr) were divided into control, sham and expremental groups (n=7)...
LCM virus antigen was visualized in infected tissue cultures and mouse tissues by the direct immunofluorescent procedure. In all instances, antigen was localized to the cytoplasm. In intracerebrally infected mice, antigen was almost completely restricted to meninges, choroid plexus, and ependyma; at no time were neurons involved. Mice infected by intraperitoneal inoculation of a viscerotropic s...
Typhoid fever and gastroenteritis caused by Salmonella enterica species are increasing globally. Pregnancy poses a high risk, but it is unclear how maternal immunity to infection is altered. In mice, susceptible strains die of S. enterica serovar typhimurium (ST) infection within 7 days whereas resistant mice (129 x 1/SvJ) develop a chronic infection. We found that virulent ST infection during ...
Chronic cytomegalovirus (CMV) infections are implicated in vascular diseases. Recently, we showed that an active mouse CMV (mCMV) infection in nonpregnant mice increased endothelial-dependent vasodilation in isolated mesenteric and uterine arteries. In late pregnancy, while increased vasodilation was found in mesenteric arteries from infected mice, there was a dramatic decrease in uterine arter...
Pregnancy is a transient immuno-compromised condition which has evolved to avoid the immune rejection of the fetus by the maternal immune system. The altered immune response of the pregnant female leads to increased susceptibility to invading pathogens, resulting in abortion and congenital defects of the fetus and a subnormal response to vaccination. Active vaccination during pregnancy may lead...
Purpose: Maternal type-1 diabetes during pregnancy causes an increased rate of malformation in fetuses.Many studies have demonstrated that an increase in the plasma level of free 02 radicals may increase the rate of abnormalities in the offspring of diabetic mothers. Because vitamin E is an active antioxidant, it may be able to decrease free 02 radicals and protect fetuses against congenital ma...
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