This acoustic study examines sound (vowel) change in apparent time across three successive generations of 123 adult female speakers ranging in age from 20 to 65 years old, representing three regional varieties of American English, typical of western North Carolina, central Ohio and southeastern Wisconsin. A set of acoustic measures characterized the dynamic nature of formant trajectories, the a...

This article concerns the classification of household sounds for the development of an application to help people with hearing disabilities to resolve everyday situations which may present them with serious problems: telephone calls, the sound of the door bell, an alarm clock, the completion of a domestic appliance programme, etc. It presents the study carried out in order to obtain the best ac...

Cell shrinkage phosphorylates and activates the Na-K-2Cl cotransporter (NKCC1), indicating the presence of a volume-sensitive protein kinase. To identify this kinase, extracts of normal and shrunken aortic endothelial cells were screened for phosphorylation of NKCC1 fusion proteins in an in-the-gel kinase assay. Hypertonic shrinkage activated a 46-kDa kinase that phosphorylated an NH2-terminal ...

The sharp affine isoperimetric inequality that bounds the volume of the centroid body of a star body (from below) by the volume of the star body itself is the Busemann-Petty centroid inequality. A decade ago, the Lp analogue of the classical BusemannPetty centroid inequality was proved. Here, the definition of the centroid body is extended to an Orlicz centroid body of a star body, and the corr...

Numerical algorithms are developed for the centroid molecular dynamics (centroid MD) method to calculate dynamical time correlation functions for general many-body quantum systems. Approaches based on the normal mode path integral molecular dynamics and staging path integral Monte Carlo methods are described to carry out a direct calculation of the force on the centroid variables in the centroi...