acute lymphoblastic leukemia (all) is the most prevalent hematological malignant tumor during childhood. unilateral infiltration into the gums is less prevalent and more often observed in the aml type. a 12-year-old girl with symptoms of pain and swelling in the buccal vestibule and also at the posterior part of the right palate of the maxilla was referred to a private dental office. the patien...

rise in temperature occurred after soil temperature was measured in different time series. in this article, ldf (logarithmic derivative filter) innovative method is applied to detect anomalies. this method tests soil temperature time series for 12 earthquakes in iran with magnitudes of either five or greater than five. results from this method were collected. based on the results of ldf method ...

how to cite this article: bhadbhade a, cheng dw. amyloid precursor protein processing in alzheimer’s disease. iranian journal of child neurology2012;6(1):1-5. alzheimer’s disease (ad) is a progressive neurodegenerative disorder and a leading cause of dementia. the ad is characterized by presence of intraneuronal tangles and extracellular plaques in the brain. the plaques are composed of dense a...

in this paper, plate-like nio nanoparticles were prepared by one-pot solid-state thermal decomposition of nickel (ii) schiff base complex as new precursor. first, the nickel (ii) schiff base precursor was prepared by solid-state grinding using nickel (ii) nitrate hexahydrate, ni(no3)2∙6h2o, and the schiff base ligand n,n′-bis-(salicylidene) benzene-1,4-diamine) for 30 min without using any solv...

The frequently occurring T-cell receptor delta (TCRD) deletions in precursor-B– acute lymphoblastic leukemia (precursorB–ALL) are assumed to be mainly caused by V 2-J rearrangements. We designed a multiplex polymerase chain reaction (PCR) assay with 61 J primers and identified clonal V 2-J rearrangements in 141 of 339 (41%) childhood and 8 of 22 (36%) adult precursor-B–ALL. A significant propor...

In childhood B-cell precursor acute lymphoblastic leukemia, cytogenetics is important in diagnosis and as an indicator of response to therapy, thus playing a key role in risk stratification of patients for treatment. Little is known of the relationship between different cytogenetic subtypes in B-cell precursor acute lymphoblastic leukemia and the recently reported copy number abnormalities affe...

We examined immunoglobulin (Ig) heavy chain, K light chain, and T cell receptor (TCR) gamma and beta gene configuration in the leukemic cells from a series of infants aged less than 1 year with acute lymphoblastic leukemia (ALL). Each of these 11 cases demonstrated leukemic cell surface antigens that have been correlated with a B cell precursor phenotype. Of the 11, lymphoblasts of 4 retained t...

We performed sensitive polymerase chain reaction–based minimal residual disease (MRD) analyses on bone marrow samples at 9 follow-up time points in 71 children with T-lineage acute lymphoblastic leukemia (T-ALL) and compared the results with the precursor B-lineage ALL (B-ALL) results (n 210) of our previous study. At the first 5 follow-up time points, the frequency of MRD-positive patients and...