نتایج جستجو برای: preaxial polydactyly

تعداد نتایج: 1274  

2005
Wayne Aitken Farshid Hajir Christian Maire

Let p be a prime number, K a number field, and S a finite set of places of K. Let KS be the compositum of all extensions of K (in a fixed algebraic closure K) which are unramified outside S, and put GK,S = Gal(KS/K) for its Galois group. These arithmetic fundamental groups play a very important role in number theory. Algebraic geometry provides the most fruitful known source of information conc...

2015
Juan Pablo Lopez Cristiana Cruceanu Laura M. Fiori Sylvie Laboissiere Isabelle Guillet Joelle Fontaine Jiannis Ragoussis Vladimir Benes Gustavo Turecki

Juan Pablo Lopez ([email protected]) Alpha Diallo ([email protected]) Cristiana Cruceanu ([email protected]) Laura M. Fiori ([email protected]) Sylvie Laboissiere ([email protected]) Isabelle Guillet ([email protected]) Joelle Fontaine ([email protected]) Jiannis Ragoussis ([email protected]) Vla...

Journal: :Development 2010
Zhen Zhang Pengfei Sui Aiwu Dong John Hassell Peter Cserjesi You-Tzung Chen Richard R Behringer Xin Sun

Preaxial polydactyly (PPD) is a common limb-associated birth defect characterized by extra digit(s) in the anterior autopod. It often results from ectopic sonic hedgehog (Shh) expression in the anterior limb bud. Although several transcription factors are known to restrict Shh expression to the posterior limb bud, how they function together remains unclear. Here we provide evidence from mouse c...

Journal: :Development 1998
Y Yang P Guillot Y Boyd M F Lyon A P McMahon

Patterning of the vertebrate limb along the anterior-posterior axis is controlled by the zone of polarizing activity (ZPA) located at the posterior limb margin. One of the vertebrate Hh family members, Shh, has been shown to be able to mediate the function of the ZPA. Several naturally occurring mouse mutations with the phenotype of preaxial polydactyly exhibit ectopic Shh expression at the ant...

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