BACKGROUND Vascular calcifications have been documented in children with end-stage renal disease. However, only a few reports have described abundant dental calculus formation in children suffering from chronic kidney disease (CKD). Moreover, dental calculus scores (DCS) and their correlation with renal disease severity have not been studied. METHODS DCS in 74 young CKD patients were evaluate...

China has experienced unprecedented urbanization since the 1980s, resulting in substantial climatic effects from local cities to broad regions. Using the Weather Research and Forecasting model dynamically coupled to an urban canopy model, we quantified the summertime climate effects of urban expansion in China's most rapidly urbanizing regions: Beijing-Tianjin-Hebei (BTH), Yangtze River Delta (...

Pelvic radiation disease (PRD) occurs in 2-11% of patients undergoing pelvic radiation for urologic and gynecologic malignancies. Hyperbaric oxygen therapy (HBOT) has previously been described as a noninvasive therapeutic option for the treatment of PRD. the purpose of study was to analyze prospectively the results of HBOT in 44 consecutive patients with PRD who were resistant to conventional o...

Purpose. To evaluate whether prophylactic circumferential retinal cryopexy (CRC) can prevent pseudophakic retinal detachment (PRD) development after posterior capsule rupture (PCR) during phacoemulsification. Methods. Retrospective patient chart analysis of eyes experiencing a PCR during phacoemulsification. Comparison of PRD development between eyes receiving CRC (cryo+ group) or not (cryo- gr...

The Ou River, a medium-sized river in the southeastern China, is examined to study estuarine turbidity maximum (ETM) response rapidly varied discharge, i.e., peak discharge (PRD). This analyzes difference ETM and sediment transport mechanisms between low-discharge PRD during neap spring tides by using Finite-Volume Community Ocean Model. three-dimensional model validated in-situ measurements fr...

BACKGROUND The intensive care unit is a dynamic environment, where high numbers of patients cared for by health care workers of different experiences and backgrounds might result in great variability in patient care. Protocol-driven interventions may facilitate timely and uniform care of common problems, like electrolyte disturbances. We prospectively compared protocol-driven (PRD) vs. physicia...

Many Drosophila developmental genes contain a DNA binding domain encoded by the homeobox. This homeodomain contains a region distantly homologous to the helix-turn-helix motif present in several prokaryotic DNA binding proteins. We investigated the nature of homeodomain-DNA interactions by making a series of mutations in the helix-turn-helix motif of the Drosophila homeodomain protein Paired (P...

A genome-wide screen revealed previously unidentified components required for transport and Golgi organization (TANGO). We now provide evidence that one of these proteins, TANGO1, is an integral membrane protein localized to endoplasmic reticulum (ER) exit sites, with a luminal SH3 domain and a cytoplasmic proline-rich domain (PRD). Knockdown of TANGO1 inhibits export of bulky collagen VII from...

The prognostic significance of delirium in hospitalized elderly has not yet been fully clarified. Objectives The present study was designed to evaluate the relationship between prevalent delirium (PrD), incident delirium (InD) and final outcome. Methods A historical cohort of 261 patients was selected. delirium was diagnosed using the Confusion Assessment Method. Results The total frequen...