The development of evidence-based guidelines has gained popularity as a strategy to reduce variation in practice and to orient clinical care around documentable best practices. Based on available data, the new European guidelines for the management of bleeding in the trauma patient do deliver a number of sound recommendations. However, some issues remain controversial and, like many guidelines,...

Social workers have the task of addressing issues that are unique to ethnic minority youth in clinical practice; however, they may be ill equipped to begin practice with these youth due to a lack of specificity within generalist curricula. Using African-American youth as an example, the paper provides evidence that there are critical areas of development and functioning that diverge from the ge...

Differing viewpoints concerning the specificity and generality of motor skill representations in memory were compared by contrasting versions of a skill having either extensive or minimal specific practice. In Experiments 1 and 2, skilled basketball players more accurately performed set shots at the foul line than would be predicted on the basis of the performance at the nearby locations, sugge...

IntroductionElectroencephalogram (EEG) is used in the neurological prognostication after cardiac arrest. “Highly malignant” EEG patterns classified according to Westhall have a high specificity for poor outcome when applied within protocols of recent studies. However, their predictive performance everyday clinical practice has not been investigated. We studied prognostic accuracy and interrater...

introduction: although extensive research has been conducted on lung cancer markers, a singular clinically applicable marker has not been found yet. the objective of this study was to evaluate the sensitivity and the specificity of carcinoembryonic antigen (cea) mrna and lung-specific x protein (lunx) mrna biomarkers in peripheral blood to detect lung cancer individually and simultaneously. met...

the work exposure conditions such as dust concentration, exposure time, use of respiratory protection devices and smoking status are effective to cause pulmonary function disorder. the objective of this study was prediction of pulmonary disorders in workers exposed to silica dust using artificial neural networks and logistic regression. a sample of 117 out of 150 workers employed in the stone c...

Perceptual learning, the improvement in performance with practice, reflects plasticity in the adult visual system. We challenge a standard claim that specificity of perceptual learning depends on task difficulty during training, instead showing that specificity, or conversely transfer, is primarily controlled by the precision demands (i.e., orientation difference) of the transfer task. Thus, fo...

BACKGROUND VELscope™ is a device designed to help detect potentially malignant disorders of the oral mucosa at an early stage using direct tissue autofluorescence. Previous research indicates a high rate of false positives using this device. This study assesses a decision making protocol for the detection of oral mucosal lesions using conventional oral examination and VELscope™ in a general den...

the use of noninvasive assessment tools such as multi-slice ct coronary angiography (msct-ca-ca) is recently considered mainly because it offers safety, patient convenience, and faster performance. the aim of the present study was to determine the ability of msct-ca-ca for the detection of significant stenoses in the coronary arteries, in comparison to conventional invasive coronary angiography...

background identification of a normal range for biomarkers, based on pregnancy outcomes (caused by their high or low values) is of special importance in clinical studies. as some pregnancy outcomes can happen in both high and low levels of biomarkers, the receiver-operating characteristic (roc) curve is unsuitable for identifying these levels separately; rather, a statistical method is preferab...