Bulky and electron-rich N-phosphinomethyl-substituted N-heterocyclic carbene transition metal complexes have been prepared in a short and efficient protocol. The modular synthesis allows one to convert borane-protected phosphino-functionalized imidazolium salts into their corresponding metal chelate complexes in a one-pot procedure.

A greener approach one-pot reaction of (2-oxo-2-phenyl-ethyl sulfanyl)-acetic acid with chalcones in presence a base to afford an unexpected (5-Benzoyl-2-hydroxy-2,4-6-triphenyl-cyclohexyl) – phenyl-methanone product. The proceeds via sequential double Michael addition-aldol mediated three consecutive C-C bonds are formed one pot. procedure has short time, easy workup, and moderate yield produc...

Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives. The catalyst was prepared by combination of chlorosulfonic acid to nano silica gel. The size of nanoparticles were observed with SEM.All prepared compounds w...

BACKGROUND The use of thromboprophylaxis to prevent clinically apparent venous thromboembolism after knee arthroscopy or casting of the lower leg is disputed. We compared the incidence of symptomatic venous thromboembolism after these procedures between patients who received anticoagulant therapy and those who received no anticoagulant therapy. METHODS We conducted two parallel, pragmatic, mu...

Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives. The catalyst was prepared by combination of chlorosulfonic acid to nano silica gel. The size of nanoparticles were observed with SEM.All prepared compounds w...

A simple procedure for the one-pot synthesis of 2,5-furandicarboxylic acid dimethyl ester (FDME) from galactaric (mucic) via carbonate (DMC) chemistry is presented. The compound was isolated as a white powder in 70% yield.

a highly efficient and environmentally friendly synthesis of various 1,5-diaryl-3-(arylamino)-1h-pyrrol-2(5h)-ones catalyzed by 1-methylpiperidinium hydrogen sulfate via one-pot cyclo-condensation reaction ofaldehydes, amines and ethyl 2-oxopropanoate under ambient conditions has been explored. the presentmethodology offers several advantages such as good yields, simple procedure, shorter react...