Recent topic of discussion on dental implants revolves around differences in titanium surface topography. According to previous studies, different chemical or mechanical processing of titanium surface would elicit diverse cell or tissue reactions. Processes such as sandblasting, acid etching, or the even newer titanium oxide surface, render to excite more osteoblasts than the previous machined ...

Introduction An exciting approach to reducing aseptic loosening of cementless implants is the stimulation and acceleration of bone ingrowth into the porous coatings of the implants. Improved fixation of components is an important factor for long term success of total hip and total knee replacement. While one method of stimulating bone formation utilizes biological agents such as BMP-2 or OP-1. ...

Porous titanium is proposed to be an effective orthopedic implant with a lower elastic modulus and supports osseointegration during implantation. To produce porous titanium, powder metallurgy (PM) assisted space-holder used in this study. Pure as the starting material, salt (NaCl) space-holder. Argon-atmospheric sintering arc plasma (APS) methods are applied for process. NaCl content was varied...

Recently, titanium compounds with one-dimensional nanostructures, such as nanotubes and nanofibers, have recently attracted much attention. Among these 1-D compounds, nanotubes composed of titanium dioxide and titanate are now being studied actively. Titanium dioxide nanotubes can be synthesized using porous anodic alumina membranes (Imai et al., 1999; Yamanaka et al., 2004), organic molecules ...

Surface modification of titanium implants is used to enhance osseointegration. The study objective was to evaluate five modified titanium surfaces in terms of cytocompatibility and pro-osteogenic/pro-angiogenic properties for human mesenchymal stromal cells: amorphous microporous silica (AMS), bone morphogenetic protein-2 immobilized on AMS (AMS + BMP), bio-active glass (BAG) and two titanium c...

In this study, we report on a group of complementary human osteoblast in vitro test methods for the preclinical evaluation of 3D porous titanium surfaces. The surfaces were prepared by additive manufacturing (electron beam melting [EBM]) and plasma spraying, allowing the creation of complex lattice surface geometries. Physical properties of the surfaces were characterized by SEM and profilometr...

Large bone defects and nonunions are serious complications that are caused by extensive trauma or tumour. As traditional therapies fail to repair these critical-sized defects, tissue engineering scaffolds can be used to regenerate the damaged tissue. Highly porous titanium scaffolds, produced by selective laser sintering with mechanical properties in range of trabecular bone (compressive streng...

Porous titanium (Ti) and Ti alloys are important scaffold materials for bone tissue engineering. In the present study, a new type of porous Ti alloy scaffold with biocompatible alloying elements, that is, niobium (Nb) and zirconium (Zr), was prepared by a space-holder sintering method. This porous TiNbZr scaffold with a porosity of 69% exhibits a mechanical strength of 67 MPa and an elastic mod...