Ionic motion through an open ion channel is analyzed within the framework of selfconsistent Brownian dynamics. A novel conceptual model in which the ions motion is coupled to the vibrations of the pore walls is introduced. The model allows to include into simulations an important additional mechanism of energy dissipation and the effects of self-induced strong modulation of the channel conducti...

Analysis of high-speed (150 frames/sec) cinematographs of the filling and expulsion of the water expulsion vesicle of Tetrahymena pyriformis shows that the vesicle fills as water is pumped into it by contractions of at least four ampullary sacs which are continuous with the endoplasmic reticulum. When filled, the vesicle is pressed against its two excretory pores by cyclotic movements of the cy...

Solutions are obtained for the stress and pore pressure due to sudden introduction of plane strain dislocations in a linear elastic, fluid-infiltrated, Biot, solid. Previous solutions have required that the pore fluid pressure and its gradient be continuous. Consequently, the antisymmetry (symmetry) ofthe pore pressure p about y = Orequires that this plane be permeable (p = 0) for a shear dislo...

A network model that investigates electrical resistivity and capillary pressure curves of oil/water/rock systems for a full̄ooded cycle (primary drainage, imbibition and secondary drainage) is presented. This model uses a realistic pore geometry in the form of a grain boundary pore (GBP) shape and pore constrictions. The model also incorporates pore-scale displacement mechanisms and pore-scale w...

This paper provides insight into the behavior of a stiffened caisson anchor under inclined cyclic loading in calcareous silt. A series tests was conducted beam centrifuge. monotonic test first performed, quantifying pure capacity, and then four varying mean load, amplitude, number cycles. Cyclic soil characterization T-bar were linked. Undrained led to generate excess pore pressure, resulting d...

Topology optimization (TopOpt) is a mathematical-driven design procedure to realize optimal material architectures. This often used automate the of devices involving flow through porous media, such as micro-fluidic devices. TopOpt offers layouts that control fluids materials, providing desired functionalities. Many prior studies in this application area have Darcy equations for primal analysis ...

Seepage force induced by ocean waves has been related to the liquefaction around submarine structure, and it shown cause significant sediment transport rapid burial of pipelines objects (Tsai et al., 2022). This study assesses impact momentary soil due pore pressure gradient near seabed generated in range oceanic coastal environment. The nonlinear wave solution stream function numerical approxi...

The permeability transition pore (PT-pore) mediates cell death through the dissipation of the mitochondrial membrane potential (ΔΨm). Because the exact composition of the PT-pore is controversial, it is crucial to investigate the actual molecular constituents and regulators of this complex. We found that mitochondrial creatine kinase-1 (CKMT1) is a universal and functionally necessary gatekeepe...