Decavanadate compounds were described to be involved in a variety of biological activities and responses such as anti-virus, anti-bacterial and anticancer. While the mechanisms of action of the antiviral and anti-bacterial activities are better understood, the same does not go for the anti-tumour activity. Nevertheless, the inhibition of tumour proliferation seems to impact certain enzymes such...

Leishmaniasis is a disease that is a significant problem for people, especially in tropical regions of the world. Current drug therapies to treat the disease are expensive, not very effective, and/or of significant side effects. A series of alkyl bisphosphonate compounds and one amino bisphosphonate compound, as well as alendronate and zoledronate, were tested as potential agents against Leishm...

The internal consistency, validity, and factor structure of the Shacham shortened version (37 items) of the 65-item profile of mood states (POMS) were examined with a sample of 428 cancer patients who were awaiting bone marrow transplantation. Cronbach's alphas ranging from 0.78 to 0.91 were obtained for each of the six subscales of the POMS-short form (POMS-SF) and for the total 37-item scale....

Despite the promising anti-cancer properties of polyoxometalates (POMs) compound, they have not yet been reported for clinical use due to their general toxicity. This study reports synthesis tocopherol succinate (TS)-polyoxomolybdate (POMo) conjugate (T2POMo) as a novel organic–inorganic hybrid POMo and evaluating its in vitro. The aim was introduce more potent derivative with less toxicity tha...

Purpose Pediatric-onset multiple sclerosis (POMS) accounts for ~5% of all multiple sclerosis cases, and has a prevalence of ~10,000 children in the USA. POMS is associated with a higher relapse rate, and results in irreversible disability on average 10 years earlier than adult-onset multiple sclerosis. Other manifestations of POMS include mental and physical fatigue, cognitive impairment, and d...

Self-assemblyings of surfactant-encapsulated Wells-Dawson polyoxometalates (SEPs) nanobuilding blocks in butanone and esters yielded supramolecular gels showing thermo and photo responsive properties. The gels can be further polymerized if unsaturated esters were used and subsequently electrospinned into nanowires and non-woven mats. The as-prepared non-woven mats have a Young's modulus as high...

BACKGROUND Currently, there is no standardised tool used to capture morbidity following abdominal aortic aneurysm (AAA) repair. The aim of this prospective observational study was to validate the Postoperative Morbidity Survey (POMS) according to its two guiding principles: to only capture morbidity substantial enough to delay discharge from hospital and to be a rapid, simple screening tool. ...

A new efficient and practical method for the room-temperature reduction of aromatic nitro compounds employing FeSO4. 7H2O, NaBH4, H3PW12O40 system in H2O under mild conditions is reported. The method is simple, inexpensive, easily scaled-up and applicable for the large scale preparation of different substituted anilines.

BACKGROUND Little is known about long-term cognitive and patient-reported outcomes of pediatric-onset multiple sclerosis (POMS). OBJECTIVE The objective of this paper is to compare cognitive and patient-reported outcomes in adults with POMS vs. adult-onset MS (AOMS). METHODS We compared standardized patient-reported measures MSQOL54, MFIS, CES-D and SDMT in adult patients with MS onset prio...

The development of bifunctional catalysts for solar-driven hydrogen and oxygen evolution has been regarded as a challenging but interesting research topic. As promising multi-electron-transfer catalysts, reported polyoxometalate (POM)-based often contain only single type transition metal substitution driving either production or evolution. Herein, viable two-step parental approach developed to ...