SYNOPSIS Single fibre electromyography was carried out in patients with polyneuropathy due to uraemia, diabetes, and alcohol. In the two former groups the fibre density within the motor unit and the impulse transmission were mainly normal. In the latter group the fibre density was significantly increased as signs of reinnervation. Impulse transmission was impaired in a number of the action pote...

Paraneoplastic polyneuropathies are among the most common distal neurological complications of systemic cancer on the nervous system. All peripheral neuropathy types, such as demyelinating, axonal, motor, sensory, or autonomic, can present in association with cancer and can have a paraneoplastic etiology (1). Classical paraneoplastic peripheral neuropathy is typically a sensory neuropathy with ...

an association between the sicca syndrome and inflammatory polyneuropathy, and lends further support to the hypothesis that, like the sicca syndrome and systemic lupus erythematosus with which they are also associated,2 the inflammatory polyneuropathies have an auto-immune basis. Our patient developed a clinical neuropathy at a time when symptoms of the sicca syndrome were minimal. This finding...

After a stay in intensive care, patients may suffer physiological after effects, such as muscle wasting, polyneuropathies, disturbed sleep, itching and poor mobility. The care that patients receive whilst on intensive care may contribute to the severity of some of these physical problems. Raising awareness amongst critical care nurses may help reduce the severity of some of the physiological af...

BACKGROUND The prevalence of hepatitis C virus (HCV) infection has been estimated at 43 to 84% in patients with essential mixed cryoglobulinaemia in recent large series. Some of these cases have been successfully treated with interferon-alpha. The objective was to evaluate the prevalence and the possible role of HCV infection in essential mixed cryoglobulinaemia. METHODS Fifteen patients (eig...

OBJECTIVES To study a representative group of patients with chronic acquired symmetric demyelinating polyneuropathies, and to evaluate classification by pattern of weakness and by presence of immunoglobulin monoclonal protein (M protein). METHODS In Vest-Agder County, Norway, an unselected population of patients with chronic symmetric polyneuropathies who fulfill electrodiagnostic criteria fo...

OBJECTIVES Previous studies of small numbers of patients have shown that antisulphatide autoantibodies are associated with polyneuropathies having a prominent sensory component. However, clinical and electrodiagnostic features are variable. The range of clinical and electrodiagnostic findings in 19 patients with polyneuropathies and high titre (> 4500) serum IgM antisulphatide antibodies is des...

We have read the case report of Oge et al. with interest (2). They evaluated the carpal tunnel range/carpal tunnel area ratio among patients with carpal tunnel syndrome and the control group, together with the median nerve area and its palmar bowing of the transverse carpal ligament. An increase in the ratio of carpal tunnel range/carpal tunnel area were detected in patients with carpal tunnel ...