We report what we believe is the first experimental confirmation at visible light wavelengths of the backscattering enhancement phenomenon of the photonic nanojet. A specially designed sample stage consisting of a multilayered sandwich of glass, solid polydimethylsiloxane (PDMS), and liquid PDMS, permitted the precise positioning of a gold nanoparticle of diameter between 50 and 100 nm within t...

Microarray devices are powerful for detecting and analyzing biological targets. However, the potential of these devices may not be fully realized due to the lack of optimization of their design and implementation. In this work, we consider a microsphere-trap array device by employing microfluidic techniques and a hydrodynamic trapping mechanism. We design a novel geometric structure of the trap...

A combined surface treatment (i.e., surface grafting and a layer-by-layer (LbL) approach) is presented to create advanced biomaterials, i.e., 3D poly(l-lactide) (PLLA) microsphere scaffolds, at room temperature. The grafted surface plays a crucial role in assembling polyelectrolyte multilayers (PEMs) onto the surface of the microspheres, thus improving the physicochemical properties of the 3D m...

PURPOSE Selective internal radiotherapy (SIRT) with yttrium-90 ((90)Y) resin microspheres can improve the clinical outcomes for selected patients with inoperable liver cancer. This technique involves intra-arterial delivery of β-emitting microspheres into hepatocellular carcinomas or liver metastases while sparing uninvolved structures. Its unique mode of action, including both (90)Y brachyther...

Classical swine fever (CSF) is a highly contagious viral disease of pigs that has a tremendous socioeconomic impact. Vaccines are available for disease control. However, most industrialized countries are implementing stamping-out strategies to eliminate the disease and avoid trade restrictions. These restrictions can be avoided through the use of marker vaccines such as CP7_E2alf. Marker vaccin...

Microplastics are ubiquitous in marine and estuarine ecosystems, thus there is increasing concern regarding exposure potential effects commercial species. To address this knowledge gap, we investigated the of microplastics on larval early juvenile life stages Black Sea Bass (Centropristis striata), a North American fishery. Larvae (13–14 days post hatch, dph) were exposed to 1.0 × 104, 105, 106...

Peptoids that are helical and partially water soluble have been shown to self-assemble into microspheres when the peptoid solution is dried on a silicon substrate. Such microsphere coatings have great potential for use in biosensor technologies, specifically to increase the surface area for binding. However, in order to be useful, the peptoids must consistently form uniform coatings. In this st...

Abstract. Various manufacturing parameters involved in ‘buoyancy method’ were inter-related. An equation based on unit cell models for a relation between volume expansion ratio (VER) of bulk microspheres in aqueous starch and microsphere size was derived. A good agreement between the equation and experimental data was found. The inter-microsphere distance (MID) concept was introduced and it was...