Ixora coccinea Linn (Rubiaceae), a small shrub cultivated throughout India, has been reported to possess a number of medicinal properties. It has traditionally been used for the treatment of diarrhea and dysentery. However the claims of Ayurveda have to be validated by suitable experimental models. The present study was therefore undertaken to evaluate the effect of aqueous extract of I. coccin...

In this study, we investigated the effect of different permeation enhancers at different concentrations viz. oleic acid, olive oil and castor oil from transdermal gel for transdermal delivery of venlafaxine, a newer antidepressant. It is a first line drug in the treatment of depression and inhibits brain serotonin and norepinephrine neuronal reuptake. It is also used in the treatment of anxiety...

Polyethylene glycol was easily grafted to silica gel and used as a solid–liquid phase transfer catalyst in the reduction of aromatic nitro compounds. This silica-grafted polyethylene glycol is proved to be an efficient heterogeneous catalyst in the reduction of nitroarenes to the corresponding aromatic amines with zinc powder in water. The reduction reactions proceeded efficiently with exce...

Large volumes of Japanese encephalitis (JE) virus propagated in mouse brain can be easily purified by polyethylene glycol 6,000. By using the polyethylene glycol precipitation method, mouse hemoglobin was almost all separated from the viral suspension, and consequently the total amount of nonviral protein in the viral suspension decreased. The recovery of infectivity was about 100%. The removal...

to determine the effects of priming and planting density on improvement of morphological and physiological traits of the two hybrid corns sc (s.c. 704) under double cropping in sari, a split plot experiment as randomized complete block design with four replications was conducted in 2010. treatments included two densities of 80 and 100 thousand plants per hectare as the first factor and osmoprim...

The objective of this in vitro study was to evaluate the antimicrobial action of sodium hypochlorite (0.25% and 0.50%) and 10% castor oil solutions against specific microorganisms, by counting Colony Forming Units (CFU) of clinically important bacteria and Candida species. Acrylic resin specimens (n = 320; Lucitone 550) were obtained from square metal matrices (10 x 10 x 2 mm), sterilized by mi...

Tacrolimus and cyclosporine have been used in various formulations, but their hypersensitivity reactions are rare in practice. Castor oil derivatives are nonionic surfactants used in aqueous preparations of hydrophobic active pharmaceutical ingredients. Castor oil derivatives that can be used as additives to tacrolimus and cyclosporine may play a role in the development of hypersensitivity reac...

Castor oil methyl esters contains nearly 90% ricinoleic acid (12-hydroxy-cis-9-octadecenoic acid). Hydrogenated castor oil methyl esters finds several applications in coating, lubricants formulations and pharmaceutical areas. The present study reports a fast, simple, efficient and continuous hydrogenation of enriched castor oil methyl ester (ECME) using 10% Pd/C catalyst at different pressures ...

The effect of the aqueous (aq) seed extract of Aframomum melegueta. K. Schum. (Zingiberaceae) on castor oil-induced diarrhea, intestinal fluid secretion, and gastrointestinal transit was investigated in the study. Castor oil (10 ml/kg, p.o.) induced copious diarrhea in all rats 3 h after treatment. Furthermore, it produced a significant increase in the volume of intestinal fluid secretion in ra...

We describe a rapid, reliable radioimmunoassay for unconjugated estriol in plasma. Polyethylene glycol (Carbowax 6000) is used to separate antibody-bound and free steroid. The assay is sensitive (25 pg for standards), precise, and accurate. At high and low concentrations of estriol, intra-assay coefficients of variation were 7.1% and 7.6%, respectively, and inter-assay coefficients of variation...