Miniemulsion homopolymerization reactions of methyl methacrylate (MMA) and styrene (STY) using poly(L-lactide) as co-stabilizer were carried out in order to prepare poly(L-lactide)/poly(methyl methacrylate) (PLLA/PMMA) and poly(L-lactide)/polystyrene (PLLA/PS) binary blend nanoparticles. The effect of PLLA concentration on methyl methacrylate (MMA) and styrene (STY) homopolymerization reactions...

Dopamine is the principle biomarker for diseases such as schizophrenia, Huntington's, and Parkinson's, and the need is urgent for rapid and sensitive detection methods for diagnosis and monitoring of such diseases. In this Article, we report a turn-on fluorescent method for rapid dopamine sensing which is based on monitoring the intrinsic fluorescence of in situ synthesized polydopamine nanopar...

The Fe(3)O(4) nanoparticles, tailored with maleimidyl 3-succinimidopropionate ligands, were conjugated with paclitaxel molecules that were attached with a poly(ethylene glycol) (PEG) spacer through a phosphodiester moiety at the (C-2')-OH position. The average number of paclitaxel molecules/nanoparticles was determined as 83. These nanoparticles liberated paclitaxel molecules upon exposure to p...

Intermetallic Pt(3)Ti nanoparticles are solubilized in water by using a generation-five, hydroxyl-terminated, poly(amidoamine) dendrimer, G5OH, as a post-synthesis surfactant. Pt(3)Ti nanoparticles, encapsulated in G5OH and dispersed over the electrode surface, exhibited a superior catalytic activity toward the electro-reduction reaction of oxygen compared to as-prepared, highly agglomerated na...

The oxidative doping of single poly(N-vinylcarbazole) (PVK) nanoparticles is reported in aqueous sodium perchlorate using the nanoimpact method. Complete oxidative doping of single PVK nanoparticles with a size of approximately 120 nm is demonstrated, showing for the first time a simple strategy to synthesize and characterize doped polymeric nanoparticles at the single nanoparticle level.

The present study examines a new dopamine sensor based on Alumina nanoparticles modified carbon paste electrode (Al2O3NPsCPE). Moreover, the present study focuses on the electrochemical act of the Al2O3NPsCPE for the detection of dopamine by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). There is also a focus on the specification of the prepared modified electrode by electroc...

Herein we propose a new structure for poly(dopamine), a synthetic eumelanin that has found broad utility as an antifouling agent. Commercially available 3-hydroxytyramine hydrochloride (dopamine HCl) was polymerized under aerobic, aqueous conditions using tris(hydroxymethyl)aminomethane (TRIS) as a basic polymerization initiator, affording a darkly colored powder product upon isolation. The pol...

Determination of Dopamine electrochemically by direct oxidation is difficult due to the co-oxidation of ascorbic acid present in high concentration in biological fluids in the same potential window. In this report, we present a non oxidative approach to electrochemically detect dopamine with high selectivity and sensitivity using our newly developed poly (anilineboronic acid ) composite with si...

biodegradable nanoparticles for aerosol therapy based on the branched polyesters, DEAPA-PVAL-g-PLGA. Pharm Res 2003; 20: 2011–2020. 17 Grenha A, Seijo B, Remunan-Lopez C. Microencapsulated chitosan nanoparticles for lung protein delivery. Eur J Pharm Sci 2005; 25: 427–437. 18 Shi LJ, Plumley CJ, Berkland C. Biodegradable nanoparticle flocculates for dry powder aerosol formulation. Langmuir 2007...