نتایج جستجو برای: poly ß
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Introduction The Lathyrus/lathyrism challenge is broad-based by its nature and requires multi-disciplinary efforts of specialists in the field of epidemiology, neurology, biochemistry, chemistry, nutrition, and agronomy. The role of chemists is in systematic determination of minor natural products in L. sativus seeds so that the sole responsibility of ß-ODAP for neurolathyrism is ascertained . ...
Therapy in nuclear medicine practice has a long distinguished history. Nuclear medicine therapy is required to be highly specific and targeted, since it always involves administration of unsealed sources of radioactivity. Most therapy agents utilize ß-particle emissions for their ability to penetrate tissues. This deposition of energy in tissue by ß emitters results in cellular damage. Among th...
Sickle cell disease (SCD) and ß-thalassemia represent the most common hemoglobinopathies caused, respectively, by the alteration of structural features or deficient production of the ß-chain of the Hb molecule. Other hemoglobinopathies are characterized by different mutations in the α- or ß-globin genes and are associated with anemia and might require periodic or chronic blood transfusions. The...
Histone methylation plays a crucial role in various biological and pathological processes including cancer development. In this study, we discovered that JARID2, an interacting component of Polycomb repressive complex-2 (PRC2) that catalyzes methylation of lysine 27 of histone H3 (H3K27), was involved in Transforming Growth Factor-beta (TGF-ß)-induced epithelial-mesenchymal transition (EMT) of ...
در این پژوهش رابطۀ خودتنظیم‌گری و تکانشوری با موفقیت ورزشی مورد‌‌بررسی قرار گرفت و نقش پیش‌بین این دو متغیر برای موفقیت ورزشی در ورزش‌های برخوردی و غیربرخوردی مقایسه شد. تعداد 223 ورزشکار حرفه‌ای (102 برخوردی و 121 غیر برخوردی) از فدراسیون‌های ورزشی به‌صورت داوطلب در این پژوهش شرکت کردند. از ورزشکاران خواسته شد مقیاس خودتنظیم‌گری (SRI-25)، مقیاس تکانشوری بارات (BIS) و مقیاس موفقیت ورزشی (SAS) ...
Chemical compounds containing the tropone structure (2,4,6-cycloheptatrien-1-one), in their molecule, called troponoids, characterized by a seven-membered ring, are distributed in some plants, bacteria and fungi, although they are relatively rare. ß-Thujaplicin (2-hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one), also known as hinokitiol, is a natural compound found in several plants of the Cup...
There is an urgent need to develop new drug treatment strategies to control the global spread of drug-sensitive and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis). The ß-lactam class of antibiotics is among the safest and most widely prescribed antibiotics, but they are not effective against M. tuberculosis due to intrinsic resistance. This study shows that 2-aminoimidazole (2...
Genetic and molecular studies have confirmed the central role of amyloid-ß production and fibrillation in the pathogenesis of Alzheimer’s disease (AD). However, the pathological pathways from amyloid-ß peptide oligomerization to the major pathological hallmarks of AD, such as neurofibrillary tangles, inflammation and loss of cholinergic neurons, are largely unknown. The innate immunity defence ...
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