Severe hypoglycemia and increased deaths were observed among two strains of endotoxin-poisoned mice within 3 to 6 hr after tryptophan injection. Sensitivity to tryptophan could be demonstrated in Rockland Farms mice by 4 hr after endotoxin and in Carworth Farms (CF-1) mice by 10 hr after endotoxin. If allopurinol was given to CF-1 mice concurrently with endotoxin, severe hypoglycemia and increa...

The potency of newly developed bispyridinium compounds (K117, K127) to reduce tabun-induced acute neurotoxic signs and symptoms was compared with currently available oxime (obidoxime) using functional observational battery. The neuroprotective effects of atropine alone and atropine combined with one of three bispyridinium oximes (K117, K127, obidoxime) on rats poisoned with tabun at a sublethal...

A random distribution of inert sites is introduced in the Ziff-Gulari-Barshad model to study the phase transitions between active and poisoned states. The adsorption of CO and O 2 molecules is not possible at the position of the inert sites. This model is investigated in the site and pair approximations, as well as through Monte Carlo simulations. We determine the mean coverages of the elements...

OBJECTIVES Poisoning by organophosphate insecticides causes cholinergic toxicity. Organophosphate induced delayed polyneuropathy (OPIDP) is a sensory-motor distal axonopathy which usually occurs after ingestion of large doses of certain organophosphate insecticides and has so far only been reported in patients with preceding cholinergic toxicity. Surprisingly, it was recently reported by other ...

The quick, easy, cheap, effective, rugged and safe (QuEChERS) method for sample preparation was applied to determine seven organophosphorus pesticides (OPs) in stomach contents of poisoned postmortem animals. The pesticides consisted of diazinon, edifenphos, ethyl p-nitrophenyl phenylphosphonothioate, fenitrothion, monocrotophos, parathion and phosphamindon, and tested samples included stomach ...

The quantities of organochlorine insecticide residues in mynas (Acridotheres tristis L.) and especially in their eggs and nestlings reflected the concentrations of these pesticides in the soil of the birds' territories. Nearly all residues were derived from contamimated invertebrates, not fruit. Samples of soil, eggs and nestlings from areas adjacent to sprayed orchards contained little pestici...

BACKGROUND Body temperature is a critical criterion of health. Drugs and a variety of poisons can affect body temperature in poisoned patients, causing hyperthermia and hyperpyrexia. OBJECTIVES Our previous study's findings in patients poisoned with organophosphate led us to the goal of this study: obtaining the initial tympanic temperature in patients poisoned by a variety of toxins. MATER...

A 48 year old patient deliberately poisoned herself with 25 g of sodium valproate and survived with supportive measures only. This case contradicts the experience of those who advocate aggressive management of such severe overdoses.