Abstract Bone loss is common in human old age and new materials that promote bone regeneration are an active line of research. In the present work, seven smart hydrogels based on PNIPAAm were synthesized with prospective to be used tissue engineering as a scaffold for growth. By changing stoichiometric concentrations reagents synthesis parameters, different physical properties morphology obtain...

Hydrogels have shown great potential for cartilage tissue engineering applications due to their capability to encapsulate cells within biomimetic, 3-dimensional (3D) microenvironments. However, the multi-step fabrication process that is necessary to produce cell/scaffold constructs with defined dimensions, limits their off-the-shelf translational usage. In this study, we have developed a hybrid...

UNLABELLED Injectable bone substitutes and techniques have been developed for use in minimally invasive procedures for bone augmentation. OBJECTIVE To develop a novel injectable thermo-sensitive alginate hydrogel (TSAH) as a scaffold to induce bone regeneration, using a minimally invasive tunnelling technique. MATERIAL AND METHODS An injectable TSAH was prepared from a copolymer solution of...