RNA polymerase II transcribes most eukaryotic genes. Photobleaching studies have revealed that living Chinese hamster ovary cells expressing the catalytic subunit of the polymerase tagged with the green fluorescent protein contain a large rapidly exchanging pool of enzyme, plus a smaller engaged fraction; genetic complementation shows this tagged polymerase to be fully functional. We investigat...

It is known that long‑term excessive administration of glucocorticoid (GC) results in osteoporosis. The present study aimed to evaluate the protective effects of Polygonum multiflorm (PM) on the bone tissue of rats with GC‑induced osteoporosis (GIO). A total of 90 6‑month‑old female Sprague Dawley rats (weight range, 190‑210 g) were randomly divided into nine groups: Control (normal saline); pr...

the possibility of fractional replacement of gelatin in pastille with either soluble, fractions or whole persian gum and the effects of olibanum gum addition on some sensory and physical properties of pastille were evaluated. findings revealed that persian gum either alone or along with high levels of sucrose could not result in gelation, whereas its insoluble part addition led to some gelation...

in order to know the environmental behaviour of toxic pollutants it is fundamental to understandthe role of chemical components of a material on sorption of such pollutants.in this study, the sorption of amix of polycyclic aromatic hydrocarbons (pahs) by cork fractions (i.e. raw cork (cf), free extractive cork(fef) and nonsaponifiable (desf)) has been investigated to better understand the role ...

rosa damascena has been found to act on central nervous system including the brain. several studies confirm that r. damascena inhibits the activity of the hypothalamus and pituitary systems in rat and can suppress the central nervous system. in traditional medicine hypnotic effect of rose is also suggested. in this study, the hypnotic effect of the ethanol crude extract of r. damascena and its ...

the aim of the present study was to investigate the effect of gender on the distribution of pancreatic islets in native chicken. ten adult male and ten adult female isfahan native chickens were used in this experiment. results showed a distinct sexual dimorphism in the native chicken pancreas which depends upon the various fractions of the pancreatic lobes, which were occupied by alpha, beta an...

to investigate the patterns of dna ploidy and proliferating activity in breast cancer and relate them to other prognostic factors, paraffin blocks of 53 cases of breast carcinoma were studied. cancer cells obtained by mechanical tissue disaggregation were examined for dna content, ploidy and s-phase fraction. dna assay was done using a cas interactive image analyzing system. all of the cases sh...

analyzed as a Latin-square design using PROC MIXED in SAS. Forage quality was analyzed as a completely random design using PROC GLM in SAS. The BMR varieties were lower (P < 0.01) in ADF and NDF at all harvest dates, while N concentrations were not affected (P > 0.41) by variety. The A fraction of DM and NDF was higher (P < 0.01) and the C fraction of DM, NDF, and ADF was lower (P < 0.01) for B...

objective(s) sonodynamic therapy is a physical treatment which utilizes ultrasound waves with an appropriate sensitizer such as protoporphyrin ix (ppix). the activation of sensitizer depends on cavitation, and therefore, high intensity ultrasound is an important necessity. beside, high intensity ultrasound can induce side effects on the healthy tissues which have surrounded tumor. the particles...

Conditions that affect the sensitivity of the Ames assay of complex hydrocarbon mixtures derived from shale oil were studied. Two fractions, one enriched in polynuclear aromatic compounds (PNA fraction), and a second fraction enriched in aromatic and heterocyclic amines (basic fraction), were selected for most of this work because of their comparatively high mutagenicity (i.e., compared with ra...