The objective of this study was to evaluate kinetics and the residual decline of tylosin in milk and plasma of lactating Najdi ewes following single intramuscular injection of tylosin at the dose of 10 mg/kg. Blood and milk samples were collected from the ewes before and at different time intervals after treatment. Tylosin concentrations were determined by microbiological agar plate assay using...

Molecular farming, or bio-pharming, has recently received much of attention for production of valuable recombinant proteins, with a few already being marketed. The use of whole plants for synthesis of pharmaceutical proteins offers various advantages in economy, scalability and safety over conventional production systems. GM plants are suitable for the inexpensive production of large amounts of...

Molecular farming, or bio-pharming, has recently received much of attention for production of valuable recombinant proteins, with a few already being marketed. The use of whole plants for synthesis of pharmaceutical proteins offers various advantages in economy, scalability and safety over conventional production systems. GM plants are suitable for the inexpensive production of large amounts of...

1. Both albumin and transferrin have been suggested as carriers of zinc in plasma. Their relative importance in Zn transport was therefore investigated as a preliminary to a study of the rates of passage of Zn through plasma. 2. The apparent log stability constant for Zn binding to human apotransferrin at pH 7.4 was estimated to be approximately 5.9 which is substantially lower than previous re...

Lymphocytes were labelled by incubation with [32P]Pi and their plasma membranes isolated. Analysis by one-dimensional and two-dimensional gel electrophoresis revealed a small number of strongly phosphorylated polypeptides. Two of these were especially prominent; they had molecular weights of about 52000 and 90000, were acidic and were apparently not glycosylated. Similar patterns were obtained ...

ACCORDING to the classical hypothesis of Starling (1896) the exchange of water and small lipid-insoluble molecules across the capillary membrane is largely governed by the balance between hydrostatic and colloid osmotic pressures, the existence of the latter being dependent upon relative impermeability of the capillary membrane to plasma proteins. Starling's concept has been verified by direct ...

Hyaline membrane disease of the newborn has been a subject of ever-growing interest to paediatricians and pathologists as it is the major cause of death in newborn babies, particularly premature ones. Much more is known of the clinical picture and physiological changes in hyaline membrane disease, or respiratory distress syndrome of the newborn (Avery, 1962; Curtis, 1957; James, 1959; Miller, 1...

In response to injury, the concentrations of several plasma proteins are characteristically altered. In part, these changes reflect an essential contribution of many of these proteins, acting in concert, to the processes involved in wound healing. There is evidence that plasma proteins support tissue repair by metabolic as well as functional activity. Specifically, plasma proteins may directly ...

It has now been generally accepted that the proteins of the plasma play an important part in protein metabolism. Madden and Whipple (1940) have shown that the plasma proteins, the reserve proteins of the body, and the tissue proteins exist in a state of dynamic equilibrium, and that they can be reversibly utilized without loss of nitrogen. They have also demonstrated the influence of food prote...

Featured Article: Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, Conrads TP, et al. The human plasma proteome: a non-redundant list developed by combination of four separate sources. Mol Cell Proteomics 2004;3:311–26. The problem of enumerating protein components in plasma has challenged the best analytical technologies for more than 80 years. The first generation of proteomics meth...