Occasionally measurement of the serumn or plasma concentration of sodium may give rise to falsely low results when carried out on a flame photometer or by an indirect reading ion selective electrode. The patients at risk are those with abnormally high serum concentrations of lipid or protein. These are, however, few: initially all low sodium concentrations as measured by flame photometry should...

Older literature has suggested that the plasma sodium concentration is not individual, that it is neither intrinsic to an individual nor reproducible, longitudinally. We recently observed that the plasma sodium concentration is heritable. Because demonstrable heritability requires individuality of the relevant phenotype, we hypothesized that the plasma sodium concentration was substantially ind...

of human plasma fluoride concentration. rg6o.-There is a constancy of plasma fluoride content of individuals who use communal water within the range O. 15-2.5 ppm fluoride. With an intake of 5.4 ppm of fluoride in the communal water there is a slight but significant elevation of the plasma concentration. There is no evidence of a marked or prolonged rise of plasma fluoride content following the...

We have read with interest the recent study by Wang et al. [1], which has been published in Medical Oncology. In this study, the authors investigated the effects on methotrexate (MTX) plasma concentrations of polymorphism rs1051296 in a miRNA binding site in solute carrier family 19, member 1 (SLC19A1), analyzing a group of 131 Chinese children with acute lymphoblastic leukemia (ALL). They conc...

Results During 2009-2011, 98 healthy children, 0-3 years old, from Bihor county, Romania, were enrolled in the study. A total of 96 children recruited were available for analysis. In the study group (n=96) the mean plasma concentration of zinc was 15.33±1.49 μmol/L. Subjects with more than 3 episodes of acute respiratory infections/year had a statistically significant lower value of plasma conc...

A B S TRA CT Plasma aldosteronie, cortisol, and renin activity were measured in nine recumbent patients with hyperaldosteronism, including seven with adenomas, one with idiopathic hyperplasia, and one with glucocorticoid suppressible hyperplasia. All had peak values of plasma aldosterone concentration from 3 a.m. to noon and lowest values at 6 p.m. or midnight. This rhythm was similar to the ci...

The plasma magnesium concentration has been determined in 73 patients with primary hyperparathyroidism. In most patients it lay within the normal range (1.7-2.3 mg./100 ml.), but in five it was less than 1.6 mg./100 ml. These patients had relatively high urinary magnesium outputs, and one of them, studied in greater detail, failed to retain parenterally administered magnesium. Hence hypomagnesa...

The cortisol response to anaesthesia and surgery was studied in 2 groups of horses undergoing either abdominal or non-abdominal surgery. The preoperative mean plasma cortisol concentration (pcc) of 381.7 nmol/l (s.d. 254.7) was markedly higher in the abdominal group than the early-morning mean pcc of 115.6 nmol/l (s.d. 78.4) in the non-abdominal group. During halothane anaesthesia and surgery t...

Ghrelin increases food intakes and body weight. Bombesin decreases food intakes and inhibits the stimulatory effect of Ghrelin on food intakes. Thyroid hormones have a crucial role in the regulation of body weight and yet the effect of bombesin on thyroid axis activity is not fully clear. Therefore, the goal of this study was to determine the effect of different doses of Ghrelin or bombesin on ...