The objective of this study was to determine the effects of a triclosan/copolymer dentifrice on plaque formation, gingivitis and gingival bleeding in pregnant subjects. This double-blind clinical study was carried out in 180 women at 3 months of pregnancy. The subjects were stratified into two balanced groups according to their baseline plaque, gingivitis and bleeding scores. Subjects received ...

The complexity of biofilm communities like dental plaque suggests that laboratory model biofilm growth systems may help to understand their structure and function. This study describes the use of a constant-depth film fermenter (CDFF) to investigate biofilm formation by a nine-membered community of oral bacteria. The community was grown to steady state in a chemostat incubated anaerobically. Th...

The assessment of immunogenicity of a diluted vaccinia vaccine for possible widespread use of a diluted vaccine in the event of a bioterrorist attack prompted us to focus on the development of a sensitive and specific plaque reduction neutralization (PRN) assay to assess the antibody response of volunteers to a vaccinia (Dryvax) vaccine. Two incubation times, 1 h or overnight (approximately 15 ...

Thrombus formation on a disrupted atherosclerotic plaque is a key event that leads to atherothrombosis. Because thrombus is induced by chemical or physical injury of normal arteries in most animal models of thrombosis, the mechanisms of thrombogenesis and thrombus growth in atherosclerotic vessels should be investigated in diseased arteries of appropriate models. Pathological findings of human ...

An improved plaque assay for dengue virus was developed utilizing baby hamster kidney (BHK-21) cells initially grown in shaker culture. Different media preparations were tested for uniform and fast formation of BHK-21 cell sheets. Several overlay formulas were tested to develop a rapid plaque assay in 6- and 24-well plastic plates. The best results were obtained utilizing Eagle minimal essentia...

Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid artery. A 2D model of different geometries is generated using CFD for NonNewtonian model. After this WSS of different geometries of stenosed arteries is calculat...

The incidence, morbid anatomy, histology, and relationship of hyaline pleural plaques to exposure to asbestos has been studied. Plaques were found in 12.3% of 334 hospital necropsies (in an urban population in Glasgow, 41 cases). In 85.3% (35 cases) asbestos bodies were found in the lungs. There is evidence of a dose-response relationship between the number of asbestos bodies found in the lungs...

Japanese encephalitis virus (JEV) formed plaques in mosquito C6/36 cell layers after adsorption on the cell surface and exposure to pH values lower than 6.2. The number of plaques decreased within pH ranges from 7.4 to 6.4, but increased within pH ranges from 6.2 to 5.8. Plaque formation was prevented by treatment of the virus with a JEV-neutralizing monoclonal antibody, 503, after virus adsorp...

To better understand these three main potential pathways for stone formation [5] , we have produced an illustration ( fig. 1 ) that depicts the site of initial mineralization along the nephron/renal pelvis, and the final location of the developing stone for each pathway. The three pathways are labeled: ‘free-particle’ stone formation, stone formation on a plug (sometimes referred to as the ‘fix...