نتایج جستجو برای: piroxicam gel

تعداد نتایج: 105822  

Journal: :iranian journal of pharmaceutical research 0
alen shahbazian department of medicinal chemistry, pharmaceutical sciences branch, islamic azad university, tehran, iran. asghar davood department of medicinal chemistry, pharmaceutical sciences branch, islamic azad university, tehran, iran alireza dabirsiaghi department of pharmaceutical sciences, pharmaceutical sciences branch, islamic azad university, tehran, iran.

piroxicam has two different crystalline forms (known as needle and cubic forms), that they are different in physicochemical properties such as biological solubility. in the current research, using taguchi experimental design approach the influences of five operating variables on formation of the piroxicam polymorph shapes in recrystallization were studied. the variables include type of solvent,...

2013
Pallab Bhattacharya Anand Kumar Pandey Sudip Paul Ranjana Patnaik Dileep R. Yavagal

BACKGROUND AND PURPOSE Aquaporin-4(AQP4) is an abundant water channel protein in brain that regulates water transport to maintain homeostasis. Cerebral edema resulting from AQP4 over expression is considered to be one of the major determinants for progressive neuronal insult during cerebral ischemia. Although, both upregulation and downregulation of AQP4 expression is associated with brain path...

2016
Deborah W. Knapp Audrey Ruple-Czerniak José A. Ramos-Vara James F. Naughton Christopher M. Fulkerson Sonia I. Honkisz

Background: Chemotherapy is expected to remain an important part of invasive urothelial carcinoma (UC) treatment. Strategies to enhance chemotherapy efficacy are needed. Objective: To determine the chemotherapy-enhancing effects of a nonselective cyclooxygenase (COX) inhibitor on vinblastine in a naturally-occurring canine model of invasive UC. Methods: With IACUC approval, privately-owned dogs...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000
R Calaluce D L Earnest D Heddens J G Einspahr D Roe C L Bogert J R Marshall D S Alberts

Prostaglandin E2 (PGE2) has served as a surrogate end point biomarker in colorectal tumor progression. Colonic mucosa PGE2 levels of patients with colorectal adenomas or carcinomas have been shown to be higher than in control subjects. Our dose-finding study on piroxicam, a nonsteroidal anti-inflammatory drug with chemopreventive effects in preclinical colon carcinoma models, suggested that 7.5...

Journal: :Physical chemistry chemical physics : PCCP 2016
Felcia Lai Jonathan J Du Peter A Williams Linda Váradi Daniel Baker Paul W Groundwater Jacob Overgaard James A Platts David E Hibbs

Experimental charge density distribution studies of two polymorphic forms of piroxicam, β-piroxicam (1) and piroxicam monohydrate (2), were carried out via high-resolution single crystal X-ray diffraction experiments and multipole refinement. The asymmetric unit of (2) consists of two discrete piroxicam molecules, (2a) and (2b), and two water molecules. Geometry differs between (1) and (2) due ...

Journal: :Stroke 1989
T Nakagomi T Sasaki T Kirino A Tamura M Noguchi I Saito K Takakura

The purpose of our study was to examine whether cyclooxygenase and lipoxygenase inhibitors ameliorate delayed neuronal death in the hippocampal CA1 sector in Mongolian gerbils after 5 minutes of forebrain ischemia. Gerbils were injected intraperitoneally with cyclooxygenase inhibitors piroxicam and flurbiprofen or with lipoxygenase inhibitors AA-861 and BW-755C. Seven days after ischemic insult...

Journal: :American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2015

Class of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), includes Anaprox (naproxen), Ansaid (flurbiprofen), Arthrotec (diclofenac sodium/misoprostil), Caldolor (ibuprofen), Cambia (diclofenac potassium), Cataflam (diclofenac), Celebrex (celecoxib), Daypro (oxaprozin), Daypro Alta (oxaprozin), Duexis (ibuprofen and famotidine), Dyloject (diclofenac), Feldene (piroxicam), Flector (diclofenac), In...

Journal: :Biomedical Journal of Scientific & Technical Research 2018

Journal: :arya atherosclerosis 0
sedigheh asgary gholam-ali naderi gholam-reza dashti zamzam paknahad

abstract objective: to investigate the effect of an anti-inflammatory drug (piroxicam) on the development of fatty streak in rabbits. methods: male rabbits were fed with four types of regimen: a) normal rabbit chow, b) 1% cholesterol diet c) cholesterol diet plus piroxicam, d) normal rabbit chow plus piroxicam. after 12 weeks, the animals were sacrificed and the aorta, as well as the right and ...

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