Pseudomonas aeruginosa is one of the most common pathogens that cause Healthcare-Associated Infections (HAIs). A previous study stated Piper betle L. extract has antibacterial activity against certain bacteria, including aeruginosa. This objective comparing methanolic and amikacin on growth used tube dilution method with a sample from Microbiology Laboratory Dr. Saiful Anwar General Hospital, M...

BACKGROUND Nuclear factor-erythroid 2 p45 related factor 2 (Nrf2) is a primary transcription factor, protecting cells from oxidative stress by regulating a number of antioxidants and phase II detoxifying enzymes. Dietary components such as sulforaphane in broccoli and quercetin in onions have been shown to be inducers of Nrf2. Piper betle (PB) grows well in tropical climate and the leaves are u...

The TLC profiles of intra- and inter-day precision for Piper betle L. (PBL) folium methanol extract was studied for their peak marker recognition and identification. The Numerical chromatographic parameters (NCPs) of the peak markers, the hierarchical clustering analysis (HCA) and the principal component analysis (PCA) were applied to authenticate the PBL. folium extract from other Piper specie...

Masks are personal protective equipment essential for COVID-19 prevention, but the use of masks has led to an increase in severity both acne (maskne) and rosacea (mask rosacea). Long-time mask-wearing can acne’s flare by modifying cutaneous facial microenvironment triggering dermatoses. To minimize this, skin needs be protected using antibacterial product. This study aimed develop determine eff...

Chronic inflammation can lead to several diseases that represent the leading causes of mortality worldwide. Conventional treatment carry some risks. Therefore, research on herbal medicine are suspected having anti-inflammatory effects, such as Piper betle L., is important. This study aims investigate effect P. L. extract nitric oxide a pro-inflammatory mediator. The dried leaves were extracted ...

Karies gigi adalah masalah utama bagi kesehatan dan rongga mulut di Indonesia, salah satu penyebabnya mikroorganisme, yaitu Streptococcus mutans. Oleh karena itu diperlukan agen antibakteri untuk mencegah perkembangannya. Belakangan ini beberapa bahan alam telah dikaji terbukti memiliki aktifitas antibakteri, diantaranya tanaman sereh (Cymbopogon citratus) sirih hijau (Piper betle L.). Peneliti...

Produksi budidaya ikan gurami membutuhkan benih yang berkualitas dan ketersediaan kontinyu, namun kendala dihadapi adalah mortalitas dalam penetasan telur kelangsungan hidup disebabkan oleh jamur Saprolegnia sp menyerang telur-telur ikan, sehingga perlu dikendalikan dengan tindakan pencegahan. Daun sirih (Piper betle. L.) merupakan salah satu bahan alami dapat dijadikan alternatif karena mengan...